FHIT protein, human

Known as: Fragile Histidine Triad Protein, Bis(5'-Adenosyl)-Triphosphatase, FHIT 
Bis(5'-adenosyl)-triphosphatase (147 aa, ~17 kDa) is encoded by the human FHIT gene. This protein is involved in nucleoside metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
0204019772017

Papers overview

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Highly Cited
2005
Highly Cited
2005
This study aimed to (a) determine if DNA methylation is a mechanism of WWOX (WW domain containing oxidoreductase) and FHIT… (More)
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Highly Cited
2001
Highly Cited
2001
Allele loss and loss of expression of fragile histidine triad (FHIT), a putative tumor suppressor gene located in chromosome… (More)
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Highly Cited
2000
Highly Cited
2000
To investigate the role of the Fhit gene in carcinogen induction of neoplasia, we have inactivated one Fhit allele in mouse… (More)
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Highly Cited
1999
Highly Cited
1999
Alteration of the FHIT (fragile histidine triad) gene occurs as an early and frequent event in lung carcinogenesis. FHIT gene… (More)
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Highly Cited
1999
Highly Cited
1999
We studied the effects of fragile histidine triad (FHIT) gene overexpression mediated by an adenoviral vector, Ad-FHIT, on cell… (More)
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Highly Cited
1998
Highly Cited
1998
We previously cloned and characterized the tumor suppressor gene FHIT (fragile histidine triad) at chromosome 3p14.2 and found… (More)
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1998
1998
Alterations in the FHIT gene at 3p14.2 occur as early and frequent events in the development of several common human cancers. The… (More)
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Highly Cited
1997
Highly Cited
1997
The candidate tumor suppressor gene, FHIT, encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal… (More)
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Highly Cited
1997
Highly Cited
1997
The FHIT gene, encoded by 10 exons in a 1.1-kb transcript, encompasses approximately 1 Mb of genomic DNA, which includes the… (More)
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Highly Cited
1996
Highly Cited
1996
Human Fhit (fragile histidine triad) protein, encoded by the FHIT putative tumor suppressor gene, is a typical dinucleoside 5',5… (More)
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