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FHIT protein, human

Known as: Fragile Histidine Triad Protein, Bis(5'-Adenosyl)-Triphosphatase, FHIT 
Bis(5'-adenosyl)-triphosphatase (147 aa, ~17 kDa) is encoded by the human FHIT gene. This protein is involved in nucleoside metabolism.
National Institutes of Health

Related topics

Related topics

6 relations
Enzyme GeneFHIT geneHydrolysisNucleotide Metabolism

Narrower (1)

bis(5'-adenosyl)-triphosphatase

Broader (1)

fragile histidine triad protein

Papers overview

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2015
2015
FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
Correction to: Oncogene (2015) 34, 2505–2515; doi:10.1038/onc.2014.184; published online 7 July 2014 Since the publication of the… 
2015
2015
FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
Correction to: Oncogene (2015) 34, 2505–2515; doi:10.1038/onc.2014.184; published online 7 July 2014 Since the online publication… 
2012
2012
HIV-TAT-fused FHIT protein functions as a potential pro-apoptotic molecule in hepatocellular carcinoma cells.
Accumulating evidence has demonstrated that FHIT (fragile histidine triad) is a bona fide tumour suppressor gene in a large… 
2011
2011
Aberrant FHIT expression is linked to bladder carcinogenesis and apoptosis.
The fragile histidine triad gene (FHIT) functions as tumor suppressor in many epithelial cell types. Although the exact… 
2006
2006
FHIT and p53 gene expression in human colonic carcinoma
Objective To investigate the expression of fragile histidine triad(FHIT)and p53 in colonic carcinoma(CC)and their relationship to… 
2005
2005
Aberrant FHIT transcripts in human colorectal cancers.
The FHIT gene, located at human chromosome 3p14.2 spanning the FRA3B common fragile region, is frequently altered in several… 
2001
2001
FHIT (fragile histidine triad) gene analysis in cervical intraepithelial neoplasia.
OBJECTIVE Recently a candidate tumor suppressor gene, FHIT (fragile histidine triad), was identified at chromosome 3p14.2… 
1998
1998
Molecular analysis of the FHIT gene in human prostate cancer
A variety of studies suggest that the FHIT gene, which encompasses the fragile site at 3p14.2, is a candidate tumor suppressor… 
1987
1987
Specific magnesium-dependent diadenosine 5',5'''-P1,P3-triphosphate pyrophosphohydrolase in Escherichia coli
A specific Mg2+-dependent bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) was purified 270-fold from Escherichia coli. The enzyme… 
1977
1977
Dinucleosidetriphosphatase from rat liver. Purification and properties.