Skip to search formSkip to main contentSkip to account menu

FGFR3 protein, human

Known as: CD333 Antigen, EC 2.7.1.112, JTK4 protein, human 
Fibroblast growth factor receptor 3 (806 aa, ~88 kDa) is encoded by the human FGFR3 gene. This protein is involved in fibroblast growth factor… 
National Institutes of Health

Related topics

Related topics

27 relations
Cell Differentiation processCell ProliferationCell Proliferation Regulatory ProcessDovitinib Lactate

Broader (1)

fibroblast growth factor receptor 3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3
FGFR3 is implicated in several human diseases. Following activation and endocytosis, FGFR3 undergoes sequential ectodomain and… 
2010
2010
Expression of Cartilage Developmental Genes in Hoxc8- and Hoxd4-Transgenic Mice
Hox genes encode transcription factors, which regulate skeletal patterning and chondrocyte differentiation during the development… 
2010
2010
Immunohistochemical Detection of Fibroblast Growth Factor Receptor 3 in Human Breast Cancer: Correlation with Clinicopathological/Molecular Parameters and Prognosis
Objective: Reportedly, fibroblast growth factor receptor 3 (FGFR3) that regulates embryonic growth and development may function… 
2008
2008
A simple "proximity" correction for Förster resonance energy transfer efficiency determination in membranes using lifetime measurements.
2006
2006
The achondroplasia mutation does not alter the dimerization energetics of the fibroblast growth factor receptor 3 transmembrane domain.
The Gly380 --> Arg mutation in the TM domain of fibroblast growth factor receptor 3 (FGFR3) of the RTK family is linked to… 
2006
2006
Enhanced skeletal growth of sheep heterozygous for an inactivated fibroblast growth factor receptor 3.
Normal fibroblast growth factor receptor 3 (FGFR3) acts as a negative bone growth regulator by restricting chondrocyte… 
Highly Cited
2005
Highly Cited
2005
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and forster resonance energy transfer suggest weak interactions between fibroblast growth factor receptor 3 (FGFR3) transmembrane domains in…
Lateral dimerization of membrane proteins has evolved as a means of signal transduction across the plasma membrane for all… 
Highly Cited
2003
Highly Cited
2003
The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3
Receptor tyrosine kinases (RTKs) such as the fibroblast growth factor receptor (FGFR) and the epidermal growth factor receptor… 
Highly Cited
2003
Highly Cited
2003
The Thanatophoric Dysplasia Type II Mutation Hampers Complete Maturation of Fibroblast Growth Factor Receptor 3 (FGFR3), Which Activates Signal Transducer and Activator of Transcription 1 (STAT1…
The K650E substitution in the fibroblast growth factor receptor 3 (FGFR3) causes constitutive tyrosine kinase activity of the… 
2002
2002
Identification and characterization of soluble isoform of fibroblast growth factor receptor 3 in human SaOS-2 osteosarcoma cells.
We have previously reported the alternatively spliced transcripts of fibroblast growth factor 3 (FGFR3 ATs and MTs) derived by… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)