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fibroblast growth factor receptor 3

Known as: Receptor, Fibroblast Growth Factor, Type 3 [Chemical/Ingredient], Receptor, Fibroblast Growth Factor, Type 3, CD333 Antigen 
A fibroblast growth factor receptor that regulates CHONDROCYTE growth and CELL DIFFERENTIATION. Mutations in the gene for fibroblast growth factor… 
National Institutes of Health

Related topics

Related topics

14 relations
AchondroplasiaFGFR3 geneFGFR3 wt AlleleIn Blood

Narrower (2)

FGFR3 protein, humanTHANATOPHORIC DYSPLASIA, TYPE I (disorder)

Broader (1)

Protein Tyrosine Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Small Peptide Modulation of Fibroblast Growth Factor Receptor 3-Dependent Postnatal Lymphangiogenesis.
BACKGROUND The fibroblast growth factor receptor (FGFR) family includes transmembrane receptors involved in a wide range of… 
2017
2017
Fibroblast Growth Factor Receptor 3 Epidermal Naevus Syndrome with Urothelial Mosaicism for the Activating p.Ser249Cys FGFR3 Mutation.
Fibroblast growth factor receptor 3 epidermal naevus syndrome (FGFR3-ENS), also known as Garcia-HafnerHapple syndrome, is a rare… 
2016
2016
Fibroblast Growth Factor Receptor 3 Deficiency Does Not Impair the Osteoanabolic Action of Parathyroid Hormone on Mice
Summary: PTH stimulates bone formation in Fgfr3 knockout mice through promotion of proliferation and differentiation in… 
2012
2012
A Phase I Study of the Safety and Pharmacokinetics of Escalating Doses of MFGR1877S, a Fibroblast Growth Factor Receptor 3 (FGFR3) Antibody, in Patients with Relapsed or Refractory t(4;14)-Positive…
Abstract 4029 Introduction: Chromosomal translocation of the FGFR3 oncogene in t(4;14)-positive multiple myeloma (MM) causes… 
2011
2011
Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3
FGFR3 is implicated in several human diseases. Following activation and endocytosis, FGFR3 undergoes sequential ectodomain and… 
2009
2009
Generation of monoclonal antibody targeting fibroblast growth factor receptor 3.
Fibroblast growth factor receptor 3 (FGFR3) is a member of the FGFR family of receptor tyrosine kinases, whose function has been… 
2007
2007
Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers.
Mutations in fibroblast growth factor receptors are known as the genetic basis of skeletal growth disorders. The mechanism of… 
2006
2006
K644E/M FGFR3 mutants activate Erk1/2 from the endoplasmic reticulum through FRS2 alpha and PLC gamma-independent pathways.
Fibroblast growth factor receptors 3 (FGFR3) with K644M/E substitutions are associated to the severe skeletal dysplasias: severe… 
2004
2004
Ectopic Fibroblast Growth Factor Receptor 3 (FGFR3) Expression Mediated by Isotype Switch Recombination.
FGFR3 is disregulated in approximately 15% of cases of multiple myeloma (MM) occurring by chromosomal translocation in the Igh… 
2001
2001
Role of FGF9 and FGF receptor 3 in osteochondroma formation.
Osteochondromas are chondro-osseous protuberances that occur in metaphyses of long bones. The cartilaginous cap is assumed to be… 
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