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FDX1 gene

Known as: FDX1, ADRENODOXIN, ADX 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
In humans, the precursor to all steroid hormones, pregnenolone, is synthesized from cholesterol by an enzyme complex comprising… Expand
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Review
2006
Review
2006
Mitochondrial P450 type enzymes catalyze central steps in steroid biosynthesis, including cholesterol conversion to pregnenolone… Expand
Highly Cited
2003
Highly Cited
2003
We report on the production of hydrocortisone, the major adrenal glucocorticoid of mammals and an important intermediate of… Expand
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Highly Cited
2003
Highly Cited
2003
Although the human sebaceous gland can synthesize cholesterol from acetate and can further metabolize steroids such as… Expand
Review
2003
Review
2003
Steroid hormone biosynthesis in the adrenal cortex and gonads involves the coordinated transcription of the genes encoding the… Expand
Highly Cited
1996
Highly Cited
1996
The neurosteroid tetrahydroprogesterone (5α-pregnan-3α-ol-20-one, allopregnanolone, THP), has been previously shown to counteract… Expand
Highly Cited
1995
Highly Cited
1995
Steroidogenic acute regulatory protein (StAR) plays a key role in steroid hormone synthesis by enhancing the metabolism of… Expand
Highly Cited
1993
Highly Cited
1993
To determine if neurosteroids (steroids synthesized in the brain) are produced by enzymes found in steroidogenic tissues, we… Expand
Highly Cited
1992
Highly Cited
1992
Quantitative autoradiography was used to evaluate the effects of adrenalectomy (ADX) and corticosterone (CORT) on binding at 5… Expand
Highly Cited
1991
Highly Cited
1991
A cDNA encoding 25‐hydroxyvitamin D3 24‐hydroxylase (P450cc24) was isolated from a rat kidney cDNA library using specific… Expand