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FASLG wt Allele

Known as: Fas Ligand Gene, Apoptosis (APO-1) Antigen Ligand 1 Gene, APTL 
Human FASLG wild-type allele is located within 1q23 and is approximately 8 kb in length. This allele, which encodes tumor necrosis factor ligand… 
National Institutes of Health

Related topics

Related topics

19 relations
1q23AKT Signaling PathwayApoptosisBystander B Cell Activation Pathway

Broader (1)

FASLG gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Functional polymorphisms in FAS/FASL system contribute to the risk of occurrence but not progression of gastric cardiac adenocarcinoma.
BACKGROUND/AIMS Loss of FAS and gain of aberrant FASL expression are common features of malignant transformation. This study was… 
2008
2008
TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells
Antigen-presenting cells (APCs) control T-cell responses by multiple mechanisms, including the expression of co-stimulatory… 
2004
2004
Rescue of death receptor and mitochondrial apoptosis signaling in resistant human NSCLC in vivo
Non small cell lung carcinoma (NSCLC) is a highly lethal malignancy that often becomes resistant to chemotherapy. To determine… 
2004
2004
CD95 polymorphisms are associated with susceptibility to MS in women A population-based study of CD95 and CD95L in MS
2001
2001
CD95 Ligand-Expressing Tumors Are Rejected in Anti-Tumor TCR Transgenic Perforin Knockout Mice
CD95 (APO-/Fas) ligand (CD95L) is a member of the TNF family predominantly expressed by activated T and NK cells but also by… 
1999
1999
Cell density modulates apoptosis in human articular chondrocytes
This study addresses the effects of cell density and serum on CD95 (APO‐1/Fas) and CD95L (Fas Ligand) expression and on the… 
1999
1999
Lymphoid cell apoptosis induced by trophoblastic cells: a model of active foeto-placental tolerance.
Highly Cited
1998
Highly Cited
1998
Oxidative stress and hypoxia/reoxygenation trigger CD95 (APO‐1/Fas) ligand expression in microglial cells
1998
1998
Interferon-α enhances CD95L-induced apoptosis of human malignant glioma cells
1997
1997
Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/CD95L interactions.
The susceptibility of Th1 and Th2 cell clones to apoptosis following HIV-gp120/CD4 cross-linking and TCR activation was… 
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