FASLG gene

Known as: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY, MEMBER 6, APT1LG1, APOPTOSIS ANTIGEN LIGAND 
This gene is an important regulator of apoptosis.
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Body fluids of cancer patients contain TEXs (tumour-derived exosomes). Tumours release large quantities of TEXs, and the protein… (More)
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Highly Cited
1999
Highly Cited
1999
Fas activation triggers apoptosis in many cell types. Studies with anti-Fas antibodies have produced conflicting results on Fas… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis-inducing Fas ligand (FasL) is a type II membrane protein, predominantly expressed in the activated T cells. FasL is… (More)
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Highly Cited
1998
Highly Cited
1998
Induction of apoptosis in keratinocytes by UV light is a critical event in photocarcinogenesis. Although p53 is of importance in… (More)
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Highly Cited
1998
Highly Cited
1998
We have previously shown that melanoma cells were resistant to apoptosis induced by TNF family members Fas ligand (FasL), TNF… (More)
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Highly Cited
1998
Highly Cited
1998
Members of the tumor necrosis factor (TNF) family such as CD95 (APO-1/Fas) ligand (L) trigger apoptosis in lymphoid cells… (More)
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Highly Cited
1998
Highly Cited
1998
Wilson's disease can result in fulminant liver failure due to hepatic copper overload. The CD95 system mediates apoptosis and has… (More)
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Highly Cited
1998
Highly Cited
1998
TRAIL (APO-2 ligand) and CD95L (CD95/APO-1/Fas ligand) share the highest homology among the TNF family members and the ability to… (More)
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Highly Cited
1997
Highly Cited
1997
To reach a clinically detectable size, neoplasms must be able to suppress or evade a host immune response. Activated T cells may… (More)
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Highly Cited
1997
Highly Cited
1997
Activation of T cells is induced efficiently by dendritic cells (DC), but little is known about the role of DC in the regulation… (More)
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