FASLG protein, human

Known as: FASL protein, human, Fas ligand (TNF superfamily, member 6), human, FAS-Ligand 
Tumor necrosis factor ligand superfamily member 6 (281 aa, ~31 kDa) is encoded by the human FASLG gene. This protein plays a role in the positive… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0102019922018

Papers overview

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2013
2013
miR-21 expression in cancer tissue has been reported to be associated with the clinical outcome and activity of gemcitabine in… (More)
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2009
2009
There are controversies about adverse effects of bisphenol A (BPA), a ubiquitous xenoestrogen, on reproduction and development of… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway… (More)
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Highly Cited
2003
Highly Cited
2003
AbstractSmall cell lung cancer cell lines were resistant to FasL and TRAIL-induced apoptosis, which could be explained by an… (More)
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Highly Cited
2001
Highly Cited
2001
We have demonstrated that Apo-2 ligand (Apo-2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis… (More)
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Highly Cited
2001
Highly Cited
2001
Human cytomegalovirus (HCMV) can suppress and evade the immune system. We have identified as a mechanism the ability of HCMV to… (More)
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Highly Cited
1999
Highly Cited
1999
Fas activation triggers apoptosis in many cell types. Studies with anti-Fas antibodies have produced conflicting results on Fas… (More)
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Highly Cited
1999
Highly Cited
1999
Suicide gene therapy systems such as the herpes simplex thymidine kinase/ganciclovir system (TK/GCV) may kill cancer cells by… (More)
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Highly Cited
1997
Highly Cited
1997
We report here that anticancer drugs such as doxorubicin lead to induction of the CD95 (APO-1/Fas) system of apoptosis and the… (More)
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Highly Cited
1997
Highly Cited
1997
The molecular mechanisms for sensitivity and resistance of tumor cells towards chemotherapy are only partially understood. In… (More)
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