FAQ

Expression Quantitative Trait Locus

Known as: eQTL 
A stretch of DNA at a particular chromosomal location that is able to regulate the expression of a specific mRNA or protein.

Topic mentions per year

Topic mentions per year

2003-2017
010020020032017

Related topics

Related topics

1 relation
Chromosomes

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Expression Quantitative Trait Locus
Chromosomes

Papers overview

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Highly Cited
2013
Highly Cited
2013
Systematic identification of trans eQTLs as putative drivers of known disease associations
Identifying the downstream effects of disease-associated SNPs is challenging. To help overcome this problem, we performed… (More)
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Highly Cited
2012
Highly Cited
2012
Patterns of Cis Regulatory Variation in Diverse Human Populations
The genetic basis of gene expression variation has long been studied with the aim to understand the landscape of regulatory… (More)
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Highly Cited
2010
Highly Cited
2010
Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
Although genome-wide association studies (GWAS) of complex traits have yielded more reproducible associations than had been… (More)
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Highly Cited
2008
Highly Cited
2008
Gene expression quantitative trait locus analysis of 16 000 barley genes reveals a complex pattern of genome-wide transcriptional regulation.
Transcript abundance from cRNA hybridizations to Affymetrix microarrays can be used for simultaneous marker development and… (More)
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Highly Cited
2008
Highly Cited
2008
Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines
Lymphoblastoid cell lines (LCLs), originally collected as renewable sources of DNA, are now being used as a model system to study… (More)
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Highly Cited
2007
Highly Cited
2007
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci.
Accessions of a plant species can show considerable genetic differences that are analyzed effectively by using recombinant inbred… (More)
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2007
2007
Accommodating pathway information in expression quantitative trait locus analysis.
The availability of high-throughput genotyping technologies and microarray assays has allowed researchers to consider pursuing… (More)
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Highly Cited
2006
Highly Cited
2006
Heritability and Tissue Specificity of Expression Quantitative Trait Loci
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression… (More)
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Highly Cited
2006
Highly Cited
2006
Tissue-specific expression and regulation of sexually dimorphic genes in mice.
We report a comprehensive analysis of gene expression differences between sexes in multiple somatic tissues of 334 mice derived… (More)
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Highly Cited
2005
Highly Cited
2005
Cis-acting expression quantitative trait loci in mice.
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross… (More)
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