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Excision Repair Cross-Complementing 1

Known as: DNA Excision Repair Protein ERCC-1, ERCC1 
DNA excision repair protein ERCC-1 (297 aa, ~33 kDa) is encoded by the human ERCC1 gene. This protein plays a role in 5-prime incision during both UV… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell NucleusDNA RepairDNA Repair EndonucleaseDNA Repair Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Tubulin, BRCA1, ERCC1, Abraxas, RAP80 mRNA expression, p53/p21 immunohistochemistry and clinical outcome in patients with advanced non small-cell lung cancer receiving first-line platinum-gemcitabine…
2011
2011
The ERCC1 N118N polymorphism does not change cellular ERCC1 protein expression or platinum sensitivity.
2011
2011
Identification of DNA repair gene Ercc1 as a novel target in melanoma
Increased expression of DNA repair genes contributes to the extreme resistance shown by melanoma to conventional DNA‐damaging… 
2009
2009
Excision repair cross-complementing 1 (ERCC1) and survival in advanced bladder cancer: Confirmatory results using immunohistochemistry.
5025 Background: DNA damaging agents are the backbone of combination chemotherapy regimens for the treatment of advanced bladder… 
2009
2009
Excision-repair cross-complementing 1 predicts response to cisplatin-based neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma.
Low excision repair cross-complementing 1 (ERCC1) has been associated with a favorable response to cisplatin (CDDP) in several… 
2009
2009
Drosophila Hold'em Is Required for a Subset of Meiotic Crossovers and Interacts With the DNA Repair Endonuclease Complex Subunits MEI-9 and ERCC1
Three Drosophila proteins, ERCC1, MUS312, and MEI-9, function in a complex proposed to resolve double-Holliday-junction… 
2008
2008
ERCC1 is required for FANCD2 focus formation.
Highly Cited
2003
Highly Cited
2003
Clear cell tumors have higher mRNA levels of ERCC1 and XPB than other histological types of epithelial ovarian cancer.
PURPOSE The purpose of the present work was to investigate the relationship between mRNA expression of ERCC1 and XPB, two key… 
Highly Cited
2000
Highly Cited
2000
Role of ERCC1 in removal of long non‐homologous tails during targeted homologous recombination
The XpF/Ercc1 structure‐specific endonuclease performs the 5′ incision in nucleotide excision repair and is the apparent… 
Highly Cited
1995
Highly Cited
1995
Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns for ERCC1 and ERCC2.
Perturbation of the DNA repair process appears to be responsible for the occurrence of a number of human diseases, which are… 
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