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Excision Repair Cross-Complementing 1
Known as:
DNA Excision Repair Protein ERCC-1
, ERCC1
DNA excision repair protein ERCC-1 (297 aa, ~33 kDa) is encoded by the human ERCC1 gene. This protein plays a role in 5-prime incision during both UV…
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National Institutes of Health
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Related topics
Related topics
10 relations
Cell Nucleus
DNA Repair
DNA Repair Endonuclease
DNA Repair Gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Tubulin, BRCA1, ERCC1, Abraxas, RAP80 mRNA expression, p53/p21 immunohistochemistry and clinical outcome in patients with advanced non small-cell lung cancer receiving first-line platinum-gemcitabine…
M. Joerger
,
D. DeJong
,
+5 authors
J. Schellens
Lung Cancer
2011
Corpus ID: 5146385
2011
2011
The ERCC1 N118N polymorphism does not change cellular ERCC1 protein expression or platinum sensitivity.
Rui Gao
,
K. Reece
,
T. Sissung
,
E. Reed
,
D. Price
,
W. Figg
Mutation research
2011
Corpus ID: 13779399
2011
2011
Identification of DNA repair gene Ercc1 as a novel target in melanoma
Liang Song
,
Ann-Marie Ritchie
,
E. M. McNeil
,
Weiling Li
,
D. Melton
Pigment Cell & Melanoma Research
2011
Corpus ID: 43197516
Increased expression of DNA repair genes contributes to the extreme resistance shown by melanoma to conventional DNA‐damaging…
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2009
2009
Excision repair cross-complementing 1 (ERCC1) and survival in advanced bladder cancer: Confirmatory results using immunohistochemistry.
M. Guix
,
L. Lema
,
+7 authors
J. Bellmunt
Journal of Clinical Oncology
2009
Corpus ID: 6371280
5025 Background: DNA damaging agents are the backbone of combination chemotherapy regimens for the treatment of advanced bladder…
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2009
2009
Excision-repair cross-complementing 1 predicts response to cisplatin-based neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma.
Koji Tanaka
,
Y. Mohri
,
+6 authors
M. Kusunoki
Molecular Medicine Reports
2009
Corpus ID: 4227780
Low excision repair cross-complementing 1 (ERCC1) has been associated with a favorable response to cisplatin (CDDP) in several…
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2009
2009
Drosophila Hold'em Is Required for a Subset of Meiotic Crossovers and Interacts With the DNA Repair Endonuclease Complex Subunits MEI-9 and ERCC1
E. Joyce
,
S. N. Tanneti
,
K. McKim
Genetics
2009
Corpus ID: 26517545
Three Drosophila proteins, ERCC1, MUS312, and MEI-9, function in a complex proposed to resolve double-Holliday-junction…
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2008
2008
ERCC1 is required for FANCD2 focus formation.
K. McCabe
,
A. Hemphill
,
+5 authors
M. Grompe
Molecular Genetics and Metabolism
2008
Corpus ID: 22859084
Highly Cited
2003
Highly Cited
2003
Clear cell tumors have higher mRNA levels of ERCC1 and XPB than other histological types of epithelial ovarian cancer.
E. Reed
,
J. Yu
,
A. Davies
,
J. Gannon
,
S. Armentrout
Clinical Cancer Research
2003
Corpus ID: 8503088
PURPOSE The purpose of the present work was to investigate the relationship between mRNA expression of ERCC1 and XPB, two key…
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Highly Cited
2000
Highly Cited
2000
Role of ERCC1 in removal of long non‐homologous tails during targeted homologous recombination
G. Adair
,
R. Rolig
,
Dana Moore‐Faver
,
Marina Zabelshansky
,
John H. Wilson
,
R. Nairn
EMBO Journal
2000
Corpus ID: 37752011
The XpF/Ercc1 structure‐specific endonuclease performs the 5′ incision in nucleotide excision repair and is the apparent…
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Highly Cited
1995
Highly Cited
1995
Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns for ERCC1 and ERCC2.
M. Dabholkar
,
M. Berger
,
+4 authors
E. Reed
Cancer Research
1995
Corpus ID: 15775913
Perturbation of the DNA repair process appears to be responsible for the occurrence of a number of human diseases, which are…
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