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Excision Repair Cross-Complementing 1

Known as: DNA Excision Repair Protein ERCC-1, ERCC1 
DNA excision repair protein ERCC-1 (297 aa, ~33 kDa) is encoded by the human ERCC1 gene. This protein plays a role in 5-prime incision during both UV… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy… Expand
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Highly Cited
2013
Highly Cited
2013
Chromosomal instability (CIN) is a hallmark of tumour initiation and progression. Some genomic regions are particularly unstable… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Excision repair cross-complementation group 1 (ERCC1) is the lead enzyme in the nucleotide excision repair process… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT Interstrand cross-links (ICLs) prevent DNA strand separation and, therefore, transcription and replication, making them… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Pivotal studies indicate a role of excision repair cross-complementation 1 (ERCC1) gene and ribonucleotide reductase… Expand
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Highly Cited
2003
Highly Cited
2003
Ovarian cancer is the leading cause of death among women from gynecological malignancies inthe United States. Resistance to the… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Overexpression of the excision repair cross-complementing 1 (ERCC1) gene, which is crucial in the repair of cisplatin… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE To test the hypotheses of whether the relative mRNA expression of the thymidylate synthase (TS) gene and the excision… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The mechanisms by which DNA interstrand cross-links (ICLs) are repaired in mammalian cells are unclear. Studies in… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE We have previously shown that relative thymidylate synthase (TS) mRNA levels in primary gastric adenocarcinomas treated… Expand
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