Excision Repair Cross-Complementing 1

Known as: DNA Excision Repair Protein ERCC-1, ERCC1 
DNA excision repair protein ERCC-1 (297 aa, ~33 kDa) is encoded by the human ERCC1 gene. This protein plays a role in 5-prime incision during both UV… (More)

Topic mentions per year

Topic mentions per year

1984-2018
05010015019842018

Papers overview

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2011
2011
PURPOSE The pemetrexed/platinum agent combination represents the standard of care in first-line treatment for malignant pleural… (More)
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2010
2010
PURPOSE We investigated the mechanism and clinical significance of the epithelial-mesenchymal transition (EMT)-induced… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Although current treatment options for metastatic non-small-cell lung cancer (NSCLC) rely on cisplatin-based chemotherapy… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND RRM1, the regulatory subunit of ribonucleotide reductase, is involved in carcinogenesis, tumor progression, and the… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Adjuvant cisplatin-based chemotherapy improves survival among patients with completely resected non-small-cell lung… (More)
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2004
2004
PURPOSE The excision repair cross-complementing 1 (ERCC1) gene is coding for a nucleotide excision repair protein involved in the… (More)
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Highly Cited
2004
Highly Cited
2004
DNA repair is a critical mechanism of resistance to platinum-based chemotherapy. Excision repair cross-complementation group 1… (More)
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Highly Cited
2003
Highly Cited
2003
Ovarian cancer is the leading cause of death among women from gynecological malignancies inthe United States. Resistance to the… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To test the hypotheses of whether the relative mRNA expression of the thymidylate synthase (TS) gene and the excision… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE We have previously shown that relative thymidylate synthase (TS) mRNA levels in primary gastric adenocarcinomas treated… (More)
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