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Equilibrative Nucleoside Transporter 1

Known as: Equilibrative Nitrobenzylmercaptopurine Riboside (NBMPR)-Sensitive Nucleoside Transporter, Equilibrative Nucleoside Transporter 1 [Chemical/Ingredient], Equilibrative NBMPR-Sensitive Nucleoside Transporter 
Equilibrative nucleoside transporter 1 (456 aa, ~50 kDa) is encoded by the human SLC29A1 gene. This protein is involved in mediating nucleoside… 
National Institutes of Health

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Cellular MembraneIn BloodIntegral Membrane ProteinsLigand Binding

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SLC29A1 protein, human

Papers overview

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2013
2013
Etoposide increases equilibrative nucleoside transporter 1 activity and fluorothymidine uptake: screening of 60 cytotoxic agents.
Equilibrative nucleoside transporter 1 (ENT1) is a major regulator for the uptake of [(18)F]fluorothymidine ([(18)F]FLT), a… 
2012
2012
Combined Analysis of Dihydropyrimidine Dehydrogenase and Human Equilibrative Nucleoside Transporter 1 Expression Predicts Survival of Pancreatic Carcinoma Patients Treated with Adjuvant Gemcitabine…
BackgroundAlthough postoperative adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PDAC) improves survival in some… 
2005
2005
Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2.
Two subtypes of equilibrative transporters, es (equilibrative inhibitor-sensitive) and ei (equilibrative inhibitor-insensitive… 
2003
2003
Correspondence Re: J. R. Mackey et al., Immunohistochemical Variation of Human Equilibrative Nucleoside Transporter 1 Protein in Primary Breast Cancers. Clin. Cancer Res., 8: 110ndash;116, 2002.
We write to update our previous report [(1)][1] of immunohistochemical analysis of frozen breast cancer samples for the hENT1[1… 
2002
2002
In vivo selection of antifolate-resistant transgenic hematopoietic stem cells in a murine bone marrow transplant model.
Currently, low levels of stable gene transfer into hematopoietic tissues of large animals and humans continues to limit the… 
1998
1998
Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells
Transfer of drug resistance genes to hematopoietic cells is being studied as a means to protect against the myelosuppression… 
1990
1990
Identification and reconstitution of the nucleoside transporter of CEM human leukemia cells.
1987
1987
Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors.
1987
1987
Purine and pyrimidine transport and permeation in human erythrocytes.
1987
1987
Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors.
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