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Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumors in adults. Uncontrolled proliferation and… Expand Binding of EphB receptors to ephrinB ligands on the surface of adjacent cells initiates signaling cascades that regulate… Expand The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The… Expand Eph receptor tyrosine kinases and their ligands, ephrins, mediate neurodevelopmental processes such as boundary formation, axon… Expand Dendritic spines show structural plasticity during development and in response to synaptic activity. We previously found that… Expand During development, Eph receptors mediate the repulsive axon guidance function of ephrins, a family of membrane attached ligands… Expand ABSTRACT Activation of the EphB2 receptor tyrosine kinase by clustered ephrin-B1 induces growth cone collapse and neurite… Expand The Eph family of receptor tyrosine kinases and the Abl family of non-receptor tyrosine kinases have both been implicated in… Expand Eph receptor tyrosine kinases play key roles in pattern formation during embryonic development, but little is known about the… Expand The sterile alpha motif (SAM) domain is a protein interaction module that is present in diverse signal-transducing proteins. SAM… Expand