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EphB2 Receptor

Known as: EphB2 Tyrosine Kinase, Receptors, EphB2, EphB2 Receptors 
An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 receptor are observed in growing AXONS and NERVE… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (6)

EPHA4 protein, humanEPHB2 protein, humanEPHB2 wt AlleleEphb2 protein, mouse
EPHB2 geneEphrin Receptor EphB1In BloodMAP kinase activity

Broader (2)

Protein Tyrosine KinaseReceptor Protein-Tyrosine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nanopatterns of Surface-Bound EphrinB1 Produce Multivalent Ligand-Receptor Interactions That Tune EphB2 Receptor Clustering.
Here we present a nanostructured surface able to produce multivalent interactions between surface-bound ephrinB1 ligands and… 
Highly Cited
2012
Highly Cited
2012
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumors in adults. Uncontrolled proliferation and… 
Highly Cited
2012
Highly Cited
2012
NMR structure of a heterodimeric SAM:SAM complex: characterization and manipulation of EphA2 binding reveal new cellular functions of SHIP2.
Highly Cited
2007
Highly Cited
2007
Ligand Binding and Calcium Influx Induce Distinct Ectodomain/γ-Secretase-processing Pathways of EphB2 Receptor*
Binding of EphB receptors to ephrinB ligands on the surface of adjacent cells initiates signaling cascades that regulate… 
Highly Cited
2007
Highly Cited
2007
Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition*
The Eph family of receptor tyrosine kinases has been implicated in tumorigenesis as well as pathological forms of angiogenesis… 
2006
2006
Release of Full-Length EphB2 Receptors from Hippocampal Neurons to Cocultured Glial Cells
Glial cells are known to actively participate in neuronal development by shaping neuronal connections through axon pruning and by… 
Highly Cited
2002
Highly Cited
2002
EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP
Dendritic spines show structural plasticity during development and in response to synaptic activity. We previously found that… 
Highly Cited
2001
Highly Cited
2001
Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor
The Eph family of receptor tyrosine kinases and the Abl family of non-receptor tyrosine kinases have both been implicated in… 
Highly Cited
2001
Highly Cited
2001
Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction
ABSTRACT Activation of the EphB2 receptor tyrosine kinase by clustered ephrin-B1 induces growth cone collapse and neurite… 
Highly Cited
2000
Highly Cited
2000
Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses
Eph receptor tyrosine kinases play key roles in pattern formation during embryonic development, but little is known about the… 
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