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Endothelin-converting enzyme 2

Known as: Endothelin Converting Enzyme 2, Endothelin Converting Metalloprotease 2, Endothelin-Converting Metalloprotease 2 
An integral membrane metalloendodpeptidase which converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond… Expand
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Clostridal neurotoxins (CNTs) are the causative agents of the neuroparalytic diseases botulism and tetanus. CNTs impair neuronal… Expand
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Highly Cited
2003
Highly Cited
2003
The abnormal accumulation of β-amyloid (Aβ) in the brain is an early and invariant feature in Alzheimer's disease (AD) and is… Expand
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Highly Cited
2002
Highly Cited
2002
The 26S proteasome mediates degradation of ubiquitin-conjugated proteins. Although ubiquitin is recycled from proteasome… Expand
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Highly Cited
2002
Highly Cited
2002
All cells have stress response pathways that maintain homeostasis in each cellular compartment. In the Gram-negative bacterium… Expand
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Highly Cited
2001
Highly Cited
2001
Deposition of β-amyloid (Aβ) peptides in the brain is an early and invariant feature of all forms of Alzheimer's disease. As with… Expand
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Highly Cited
1999
Highly Cited
1999
Signaling by the Notch surface receptor controls cell fate determination in a broad spectrum of tissues. This signaling is… Expand
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Highly Cited
1999
Highly Cited
1999
Metalloprotease disintegrins (a disintegrin and metalloprotease (ADAM) and metalloprotease, disintegrin,cysteine-rich proteins… Expand
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Highly Cited
1996
Highly Cited
1996
It has long been suspected that proteolytic activity associated with advancing growth cones may be required for axon extension… Expand
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Highly Cited
1995
Highly Cited
1995
Endothelins (ET) are a family of potent vasoactive peptides that are produced from biologically inactive intermediates, termed… Expand
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Highly Cited
1994
Highly Cited
1994
Endothelin-1 (ET-1), a 21-residue vasoactive peptide, is produced in vascular endothelial cells from the 38-residue inactive… Expand
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