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Endothelin-converting enzyme 2

Known as: Endothelin Converting Enzyme 2, Endothelin Converting Metalloprotease 2, Endothelin-Converting Metalloprotease 2 
An integral membrane metalloendodpeptidase which converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond… 
National Institutes of Health

Related topics

Related topics

2 relations
ECE2 gene

Broader (1)

Endothelin-Converting Enzymes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
The Secreted Metalloprotease ADAMTS20 Is Required for Melanoblast Survival
ADAMTS20 (A disintegrin-like and metalloprotease domain with thrombospondin type-1 motifs) is a member of a family of secreted… 
Highly Cited
2007
Highly Cited
2007
Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues.
Review
2006
Review
2006
β-Amyloid Degradation and Alzheimer's Disease
Extensive β-amyloid (Aβ) deposits in brain parenchyma in the form of senile plaques and in blood vessels in the form of amyloid… 
Highly Cited
2005
Highly Cited
2005
Reduction of the Disintegrin and Metalloprotease ADAM12 in Preeclampsia
Objectives: The secreted form of ADAM12 is a metalloprotease that may be involved in placental and fetal growth. We examined… 
Highly Cited
2004
Highly Cited
2004
Substrate recognition strategy for botulinum neurotoxin serotype A
Clostridal neurotoxins (CNTs) are the causative agents of the neuroparalytic diseases botulism and tetanus. CNTs impair neuronal… 
Highly Cited
2003
Highly Cited
2003
Alzheimer's Disease β-Amyloid Peptide Is Increased in Mice Deficient in Endothelin-converting Enzyme*
The abnormal accumulation of β-amyloid (Aβ) in the brain is an early and invariant feature in Alzheimer's disease (AD) and is… 
Highly Cited
2001
Highly Cited
2001
Degradation of the Alzheimer's Amyloid β Peptide by Endothelin-converting Enzyme*
Deposition of β-amyloid (Aβ) peptides in the brain is an early and invariant feature of all forms of Alzheimer's disease. As with… 
Highly Cited
1999
Highly Cited
1999
Interaction of the Metalloprotease Disintegrins MDC9 and MDC15 with Two SH3 Domain-containing Proteins, Endophilin I and SH3PX1*
Metalloprotease disintegrins (a disintegrin and metalloprotease (ADAM) and metalloprotease, disintegrin,cysteine-rich proteins… 
Highly Cited
1996
Highly Cited
1996
The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila.
It has long been suspected that proteolytic activity associated with advancing growth cones may be required for axon extension… 
Highly Cited
1995
Highly Cited
1995
17 beta-estradiol stimulates prostacyclin, but not endothelin-1, production in human vascular endothelial cells.
The exact mechanisms by which estrogens protect against occlusive vascular disorders are not known. One possibility could be an… 
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