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Endothelin-Converting Enzymes

Known as: Endothelin Converting Enzyme, Endothelin Converting Enzymes, Endothelin-Converting Enzyme 
Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1.
National Institutes of Health

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Endothelin Converting Enzyme-1aEndothelin-Converting Enzyme-1bEndothelin-converting enzyme 1Endothelin-converting enzyme 2
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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Review
2006
Review
2006
CGS 35601, a triple inhibitor of angiotensin converting enzyme, neutral endopeptidase and endothelin converting enzyme.
CGS 35601 (L-tryptophan, N-[[1-[[(2S)-2-mercapto-4-methyl-1-oxopentyl]amino]-cyclopentyl]carbonyl]) is one of a few single… 
2006
2006
Expression of endothelin-converting enzyme, endothelin-1 and endothelin receptors at the site of percutaneous coronary intervention in humans
Objective The repair process at the site of injury after percutaneous coronary intervention (PCI) is dominated by neointimal… 
Review
2002
Review
2002
Proinflammatory effects of angiotensin II and endothelin: targets for progression of cardiovascular and renal diseases
Angiotensin II and endothelin-1 can both be regulated by nuclear factor-κB. They are to varying degrees also capable of… 
Review
2000
Review
2000
Endothelin-converting enzyme inhibitors: current status and perspectives.
Recent research has led to the discovery of potent selective or mixed endothelin-converting enzyme (ECE), ECE/neutral… 
Highly Cited
1999
Highly Cited
1999
Neonatal Lethality in Mice Deficient in XCE, a Novel Member of the Endothelin-converting Enzyme and Neutral Endopeptidase Family*
XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in specific… 
1999
1999
Endothelin B receptor-deficient rats as a subtraction model to study the cerebral endothelin system
1998
1998
Design and synthesis of potent, selective inhibitors of endothelin-converting enzyme.
Endothelin-1 is the most potent peptidic vasoconstrictor discovered to date. The final step of posttranslational processing of… 
1996
1996
Metallopeptidase inhibitors induce an up-regulation of endothelin-converting enzyme levels and its redistribution from the plasma membrane to an intracellular compartment.
Endothelin-converting enzyme is a phosphoramidon-sensitive membrane metallopeptidase that catalyses the final step in… 
Highly Cited
1995
Highly Cited
1995
Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
Endothelin (ET)-2 is a 21 residue vasoactive peptide which is biosynthesized from big ET-2(1-38) by a specific cleavage at Trp21… 
1993
1993
Pharmacological profiles of aspergillomarasmines as endothelin converting enzyme inhibitors.
Aspergillomarasmine-A and -B (AM-A and -B), which were isolated from the cultured broth of an unidentified fungus N877, showed… 
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