Endothelin-Converting Enzymes

Known as: Endothelin Converting Enzyme, Endothelin Converting Enzymes, Endothelin-Converting Enzyme 
Metalloendopeptidases which convert BIG ENDOTHELIN to ENDOTHELIN-1.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
The deposition of beta-amyloid in the brain is a pathological hallmark of Alzheimer disease (AD). Normally, the accumulation of… (More)
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Highly Cited
2003
Highly Cited
2003
The abnormal accumulation of beta-amyloid (Abeta) in the brain is an early and invariant feature in Alzheimer's disease (AD) and… (More)
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Highly Cited
2001
Highly Cited
2001
Deposition of beta-amyloid (Abeta) peptides in the brain is an early and invariant feature of all forms of Alzheimer's disease… (More)
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Highly Cited
2001
Highly Cited
2001
An imbalance of nitric oxide and endothelin plays an important role in cardiovascular disease. Thrombin exerts profound effects… (More)
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Highly Cited
1997
Highly Cited
1997
Angiotensin II (Ang II)-stimulated expression of endothelin-1 (ET-1) mRNA is blocked by ETA antagonists in vitro. We studied… (More)
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Review
1996
Review
1996
A critical processing step in endothelin biosynthesis is the conversion of the intermediate "big endothelin" to its biologically… (More)
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Highly Cited
1994
Highly Cited
1994
Endothelin-1 (ET-1), a 21-residue vasoactive peptide, is produced in vascular endothelial cells from the 38-residue inactive… (More)
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Highly Cited
1994
Highly Cited
1994
Endothelin-1 is an endothelium-derived vasoconstrictor peptide, possibly involved in the pathophysiology of cardiovascular… (More)
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Highly Cited
1994
Highly Cited
1994
Endothelin (ET) is a 21-residue potent vasoconstrictive peptide produced by vascular endothelial cells and formed from its… (More)
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Highly Cited
1988
Highly Cited
1988
Since the discovery of endothelium-dependent vasodilation, vascular endothelium has been recognized as an important functional… (More)
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