EXO1 gene

Known as: rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1, HEX1, exonuclease 1 
This gene plays a role in DNA metabolic processes during stromal differentiation.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Repair of dsDNA breaks requires processing to produce 3'-terminated ssDNA. We biochemically reconstituted DNA end resection using… (More)
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Highly Cited
2011
Highly Cited
2011
Repair of DNA double-strand breaks (DSBs) by homologous recombination requires resection of 5′-termini to generate 3′-single… (More)
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Highly Cited
2010
Highly Cited
2010
Single-stranded DNA constitutes an important early intermediate for homologous recombination and damage-induced cell cycle… (More)
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Highly Cited
2008
Highly Cited
2008
DNA ends exposed after introduction of double-strand breaks (DSBs) undergo 5′–3′ nucleolytic degradation to generate single… (More)
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Highly Cited
2008
Highly Cited
2008
Formation of single-strand DNA (ssDNA) tails at a double-strand break (DSB) is a key step in homologous recombination and DNA… (More)
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Highly Cited
2008
Highly Cited
2008
Exo1 is a nuclease involved in mismatch repair, DSB repair, stalled replication fork processing and in the DNA damage response… (More)
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Highly Cited
2005
Highly Cited
2005
The replication checkpoint coordinates the cell cycle with DNA replication and recombination, preventing genome instability and… (More)
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Highly Cited
2002
Highly Cited
2002
We have examined the role of checkpoint pathways in responding to a yku70Delta defect in budding yeast. We show that CHK1, MEC1… (More)
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Highly Cited
2000
Highly Cited
2000
The MRE11, RAD50, and XRS2 genes of Saccharomyces cerevisiae are involved in the repair of DNA double-strand breaks (DSBs… (More)
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Highly Cited
1997
Highly Cited
1997
A two-hybrid screen was used to identify Saccharomyces cerevisiae genes encoding proteins that interact with MSH2. One gene was… (More)
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