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EXO1 protein, human

Known as: Hex1 protein, human, Exonuclease I, EXOI protein, human 
Exonuclease 1 (846 aa, ~94 kDa) is encoded by the human EXO1 gene. This protein is involved in DNA exonuclease activity, 5' overhang removal and… 
National Institutes of Health

Related topics

Related topics

12 relations
5'-3'-ExonucleasesDNA RepairDNA Repair GeneEXO1 gene

Broader (3)

DNA Repair EnzymesExodeoxyribonuclease Iexodeoxyribonuclease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Exonuclease-1 interactswith the transcriptional co-repressor KAP 1
Error-free repair of DNA double-strand break is orchestrated by homologous recombination pathways and requires the concerted… 
2017
2017
Redundancy between nucleases required for homologous recombination promotes PARP inhibitor resistance in the eukaryotic model organism Dictyostelium
Abstract ADP-ribosyltransferases promote repair of DNA single strand breaks and disruption of this pathway by Poly(ADP-ribose… 
Review
2011
Review
2011
An Anti-Checkpoint Activity for Rif1
Chromosomal double-strand breaks (DSBs) are among the most severe lesions a cell has to deal with: if left unrepaired, they may… 
2008
2008
Inhibition of the 5′ to 3′ exonuclease activity of hEXO1 by 8‐oxoguanine
The mismatch repair pathway is responsible for maintaining genomic stability by correcting base‐base mismatches and insertion… 
2007
2007
Synergistic effect of TRM2/RNC1 and EXO1 in DNA double-strand break repair in Saccharomyces cerevisiae
In our recently published study, we provided in vitro as well as in vivo data demonstrating the involvement of TRM2/RNC1 in… 
2005
2005
Research Highlights
  • Nature Structural &Molecular Biology
  • 2005
  • Corpus ID: 41613164
Membrane trafficking in the cell is a highly regulated process. One pathway in which these trafficking events are found is… 
2003
2003
Different frameshift mutation spectra in non-repetitive DNA of MutSalpha- and MutLalpha-deficient fission yeast cells.
A frameshift reversion assay has been established for Schizosaccharomyces pombe, which allows detection of deletions and… 
2001
2001
Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors.
The mismatch repair (MMR) system ensures genome integrity by removing mispaired and unpaired bases that originate during… 
1998
1998
Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1
Abstract Besides the MutLS-like system, Schizosaccharomyces pombe has an additional pathway of mismatch repair. This minor… 
1998
1998
Isolation of the gene and characterization of the enzymatic properties of a major exoglucanase of humicola grisea without a cellulose-binding domain.
An exoglucanase gene was cloned from a cellulolytic fungus, Humicola grisea. DNA sequencing of this gene, designated as exo1… 
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