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ERCC5 protein, human

Known as: XPG-Complementing Protein, XPGC protein, human, XPG protein, human 
DNA repair protein complementing XP-G cells (1186 aa, ~133 kDa) is encoded by the human ERCC5 gene. This protein plays a role in the repair of UV… 
National Institutes of Health

Related topics

Related topics

8 relations
Cerebrooculofacioskeletal Syndrome 1Cockayne SyndromeDNA RepairDNA Repair Endonuclease

Papers overview

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2012
2012
DNA repair gene variants in endometrial carcinoma
Several polymorphisms in the DNA repair gene are thought to have significant effects on cancer risk. In this study, we… 
2007
2007
Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage.
Highly Cited
2006
Highly Cited
2006
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen
The cyclin-dependent kinase inhibitor p21CDKN1A plays a fundamental role in the DNA-damage response by inducing cell-cycle arrest… 
2005
2005
Increased DNA breaks and up-regulation of both G1 and G2 checkpoint genes p21WAF1/CIP1 and 14-3-3 σ in circulating leukocytes of glaucoma patients and vasospastic individuals
Summary.Objective: Vascular disorder leading to local ischemia/reperfusion has been shown to play an important role in the… 
2004
2004
DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster.
A novel endo-exonuclease, DmGEN (Drosophila Melanogaster XPG-like endonuclease), was identified in D.melanogaster. DmGEN is… 
Highly Cited
2003
Highly Cited
2003
Tumor suppressor p53 dependent recruitment of nucleotide excision repair factors XPC and TFIIH to DNA damage.
Review
2003
Review
2003
Transcription-coupled repair of 8-oxoguanine in human cells and its deficiency in some DNA repair diseases.
2003
2003
In Vitro and in Vivo Dimerization of Human Endonuclease III Stimulates Its Activity*
Human endonuclease III (hNTH1), a DNA glycosylase with associated abasic lyase activity, repairs various mutagenic and toxic… 
Highly Cited
2000
Highly Cited
2000
Altered gene expression in lymphocytes of patients with normal-tension glaucoma
Background. In glaucoma there is a loss of retinal ganglion cells. There is evidence that this loss can occur by apoptosis. The… 
1999
1999
Inverse correlation between p53 protein levels and DNA repair efficiency in human fibroblast strains treated with 4-nitroquinoline 1-oxide: evidence that lesions other than DNA strand breaks trigger…
Ionizing radiation-induced stabilization and the resultant transient accumulation of the p53 tumor suppressor protein is impaired… 
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