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ELAC2 gene

Known as: elaC ribonuclease Z 2, tRNase Z (long form), ELAC2 
This gene plays a role in the processing of transfer RNA.
National Institutes of Health

Related topics

Related topics

4 relations
ELAC2 protein, humanHydrolysisRNA DegradationRNA Processing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Prevalence of the Ser217Leu Variant of the ELAC2 Gene and Its Association with Prostate Cancer in Population of the Littoral Region of Cameroon
Background. HPC2/ELAC2 has been identified as a prostate cancer (PC) susceptibility gene. Ser- Leu changes at amino acid 217 have… 
2016
2016
Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail.
PC2 (polycystin-2) forms a Ca(2+)-permeable channel in the cell membrane and its function is regulated by cytosolic Ca(2+) levels… 
2015
2015
A Novel WRN Frameshift Mutation Identified by Multiplex Genetic Testing in a Family with Multiple Cases of Cancer
Next-generation sequencing technology allows simultaneous analysis of multiple susceptibility genes for clinical cancer genetics… 
2014
2014
Risk Factors for Prostate Cancer
New research suggests that age, race and family history are the biggest risk factors for a man to develop prostate cancer… 
2008
2008
Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study.
Two non-synonymous single-nucleotide polymorphisms (SNPs), Ser217Leu and Ala541Thr, in the elaC homolog 2 (Escherichia coli… 
Review
2006
Review
2006
Molecular biology in prostate cancer
SummaryGenes involved in cancer generation are usually tumor suppressors and oncogenes. Progressive genetic alterations in these… 
2004
2004
Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer
Three putative prostate cancer–susceptibility genes, RNASEL/HPC1 at 1q24, MSR1 at 8p22, and ELAC2/HPC2 at 17p11, have recently… 
Review
2004
Review
2004
Structure of primate and rodent orthologs of the prostate cancer susceptibility gene ELAC2.
2001
2001
Prostate cancer: simplicity to complexity
Prostate cancer is a complex disease to which a multitude of genetic and environmental factors contribute. Two new studies offer… 
Highly Cited
1997
Highly Cited
1997
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here… 
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