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EIF4EBP1 protein, human

Known as: PHAS-I, 4E-BP1, Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 
Eukaryotic translation initiation factor 4E-binding protein 1 (118 aa, ~13 kDa) is encoded by the human EIF4EBP1 gene. This protein is involved in… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

Adaptor Proteins, Signal TransducingEIF4EBP1 wt AllelePhosphoproteins
Binding ProteinsEIF4EBP1 geneERBB Family Signaling PathwayG1/S Transition Checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Discrete Metal Catalysts for Stereoselective Ring-Opening Polymerization of Chiral Racemic β-Lactones.
Poly(β-hydroxyalkanoate)s (PHAs) are a class of aliphatic polyesters that can be efficiently synthesized by ring-opening… 
Highly Cited
2010
Highly Cited
2010
New Hierarchical Phosphorylation Pathway of the Translational Repressor eIF4E-binding Protein 1 (4E-BP1) in Ischemia-Reperfusion Stress*
Eukaryotic initiation factor (eIF) 4E-binding protein 1 (4E-BP1) is a translational repressor that is characterized by its… 
Highly Cited
2009
Highly Cited
2009
Specific Activation of mTORC1 by Rheb G-protein in Vitro Involves Enhanced Recruitment of Its Substrate Protein*
Rheb G-protein plays critical roles in the TSC/Rheb/mTOR signaling pathway by activating mTORC1. The activation of mTORC1 by Rheb… 
Highly Cited
2006
Highly Cited
2006
Assembly of an active translation initiation factor complex by a viral protein.
Recruitment of the 40S ribosome to the 5' end of a eukaryotic mRNA requires assembly of translation initiation factors eIF4E, the… 
Highly Cited
2002
Highly Cited
2002
Translational Control of Cell Fate: Availability of Phosphorylation Sites on Translational Repressor 4E-BP1 Governs Its Proapoptotic Potency
ABSTRACT Translational control has been recently added to well-recognized genomic, transcriptional, and posttranslational… 
Highly Cited
2001
Highly Cited
2001
Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells.
BACKGROUND Augmented protein translation by insulin involves activation of eukaryotic initiation factor 4E (eIF4E) that follows… 
Highly Cited
1998
Highly Cited
1998
Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111).
The effects of insulin and rapamycin on the phosphorylation of the translation regulator, initiation factor 4E-binding protein 1… 
Highly Cited
1996
Highly Cited
1996
Regulation of Both Glycogen Synthase and PHAS-I by Insulin in Rat Skeletal Muscle Involves Mitogen-activated Protein Kinase-independent and Rapamycin-sensitive Pathways (*)
Incubating rat diaphragm muscles with insulin increased the glycogen synthase activity ratio (minus glucose 6-phosphate/plus… 
Highly Cited
1996
Highly Cited
1996
Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle.
We have investigated the roles of eukaryotic initiation factor 4E (eIF-4E), the cap-binding protein, and the translational… 
Highly Cited
1981
Highly Cited
1981
Pancreatic carcinoma in azaserine‐treated rats: Induction, classification and dietary modulation of incidence
Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150–520 mg/kg by… 
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