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EDNRB wt Allele

Known as: ET-B, WS4A, ET-BR 
Human EDNRB wild-type allele is located in the vicinity of 13q22 and is approximately 24 kb in length. This allele, which encodes endothelin B… 
National Institutes of Health

Related topics

Related topics

5 relations
G Protein-Coupled Receptor SignalingLigand BindingMelanogenesis PathwayReceptor Signaling

Papers overview

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Highly Cited
2005
Highly Cited
2005
Evaluation of the RET regulatory landscape reveals the biological relevance of a HSCR-implicated enhancer.
Evolutionary sequence conservation is now a relatively common approach for the prediction of functional DNA sequences. However… 
Highly Cited
2003
Highly Cited
2003
Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).
The activation of the RET signaling pathway during embryogenesis is a crucial prerequisite for a directional migration of enteric… 
Highly Cited
2000
Highly Cited
2000
RET genotypes comprising specific haplotypes of polymorphic variants predispose to isolated Hirschsprung disease
BACKGROUND Hirschsprung disease (HSCR), which may be sporadic or familial, occurs in 1:5000 live births and presents with… 
Highly Cited
1997
Highly Cited
1997
Permissive Role of Nitric Oxide in Endothelin-induced Migration of Endothelial Cells*
Endothelin (ET) synthesis is enhanced at sites of ischemia or in injured vessels. The purpose of this study was to explore the… 
Highly Cited
1997
Highly Cited
1997
Presence of contractile endothelin-A and dilatory endothelin-B receptors in human cerebral arteries.
OBJECTIVE The aim of the present study was to elucidate the endothelin receptor subtypes responsible for the endothelin-induced… 
Highly Cited
1997
Highly Cited
1997
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats.
Highly Cited
1996
Highly Cited
1996
Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater
Highly Cited
1996
Highly Cited
1996
Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction
Objective To determine the quantitative roles played by the different vasoconstrictor systems in the acute pressor response in… 
Highly Cited
1993
Highly Cited
1993
Endothelin receptors in cultured adult rat cardiac fibroblasts.
OBJECTIVES Endothelins, released by vascular endothelial cells, are known growth promoters of various mesenchymal cells that… 
Highly Cited
1992
Highly Cited
1992
Discrimination between ETA‐ and ETB‐receptor‐mediated effects of endothelin‐1 and [Ala1,3,11,15]endothelin‐1 by BQ‐123 in the anaesthetized rat
1 The influence of BQ‐123 (a selective ETA‐receptor antagonist) on the haemodynamic response elicited by endothelin‐1 (ET‐1) and… 
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