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ECT2 gene

Known as: ECT2, ARHGEF31, epithelial cell transforming 2 
This gene plays a role in both GTPase-mediated signaling and cellular stress responses.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The biological impact of Rho depends critically on the precise subcellular localization of its active, GTP-loaded form. This can… Expand
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Highly Cited
2012
Highly Cited
2012
Summary As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify… Expand
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Highly Cited
2006
Highly Cited
2006
During determination of the cell division plane, an actomyosin contractile ring is induced at the equatorial cell cortex by… Expand
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Highly Cited
2006
Highly Cited
2006
In anaphase, microtubules provide a specification signal for positioning of the contractile ring. However, the nature of the… Expand
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Highly Cited
2006
Highly Cited
2006
We applied genetic tools available in Drosophila to identify candidate substrates of the UBE3A ubiquitin ligase, the gene… Expand
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Highly Cited
2005
Highly Cited
2005
In anaphase, the spindle dictates the site of contractile ring assembly. Assembly and ingression of the contractile ring involves… Expand
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Highly Cited
2005
Highly Cited
2005
Initiation of cytokinesis requires the establishment of the cleavage plane, the assembly of the contractile ring, and the… Expand
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Highly Cited
1999
Highly Cited
1999
Animal cells divide into two daughter cells by the formation of an actomyosin-based contractile ring through a process called… Expand
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Highly Cited
1997
Highly Cited
1997
Computer analysis of a conserved domain, BRCT, first described at the carboxyl ter‐minus of the breast cancer protein BRCA1, a… Expand
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Highly Cited
1993
Highly Cited
1993
WE have developed an efficient expression cloning system that allows rapid isolation of complementary DNAs able to induce the… Expand
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