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ECT2 gene

Known as: ECT2, ARHGEF31, epithelial cell transforming 2 
This gene plays a role in both GTPase-mediated signaling and cellular stress responses.
National Institutes of Health

Related topics

Related topics

5 relations
CytokinesisECT2L genePositive Regulation of ApoptosisProtein ECT2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 4235: Phosphorylation of Serine 861 in the ECT2 guanine nucleotide exchange factor activates Rho family GTPases and is a biomarker for several tumor types
2017
2017
ECT2-Dependent rRNA Synthesis Is Critical for Lung Cancer Oncogenesis.
ECT2 mediates Kras-Trp53-driven lung adenocarcinoma initiation and transformed growth. 
2016
2016
Control of cleavage furrow formation by the RhoGEF Ect2
Cytokinesis is the final step of cell division that physically separates the cytoplasm of nascent daughter cells. The mitotic… 
2015
2015
Up-regulation of ECT 2 is associated with poor prognosis in gastric cancer patients
Objectives: The aim of this study was to investigate the expression of ECT2 in gastric cancer and its clinical significance… 
2015
2015
Iconography : Elevated expression of ECT2 predicts unfavorable prognosis in patients with colorectal cancer
2015
2015
Significance and the expression of ECT2 mRNA and protein in peripheral blood with gastric cancer
Objective: To explore the expression and significance of ECT2 mRNA and protein in peripheral blood of patients with gastric… 
2014
2014
The Role Of ECT2 In Astroctyoma Invasion and Stress Granule Formation
2012
2012
Abstract LB-30: A functional analysis of the nuclear RhoGEF Ect2 in ovarian cancer
Ect2 is a guanine nucleotide exchange factor (GEF) and activator of Rho family small GTPases. Ect2 regulates RhoA, Rac1, and… 
2008
2008
Abstract 1362: The Rho Guanine Exchange Factor ECT2 is Upregulated in a Stretch-Dependent Manner in Arteries of Hypertensive Rats and Contributes to Cell Proliferation
2000
2000
Rho GTPase のヌクレオチド交換因子 ECT2 による細胞のがん化と細胞分裂の制御
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