ECT2 gene

Known as: ECT2, ARHGEF31, epithelial cell transforming 2 
This gene plays a role in both GTPase-mediated signaling and cellular stress responses.
National Institutes of Health

Papers overview

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2013
2013
Osteosarcoma is one of the most common tumors. The mechanisms of formation and development of osteosarcoma have been studied for… (More)
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Highly Cited
2012
Highly Cited
2012
As they enter mitosis, animal cells undergo profound actin-dependent changes in shape to become round. Here we identify the Cdk1… (More)
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2008
2008
Cytokinesis is a highly regulated and dynamic event that involves the reorganization of the cytoskeleton and membrane… (More)
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Highly Cited
2006
Highly Cited
2006
During determination of the cell division plane, an actomyosin contractile ring is induced at the equatorial cell cortex by… (More)
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2006
2006
We applied genetic tools available in Drosophila to identify candidate substrates of the UBE3A ubiquitin ligase, the gene… (More)
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Highly Cited
2005
Highly Cited
2005
In anaphase, the spindle dictates the site of contractile ring assembly. Assembly and ingression of the contractile ring involves… (More)
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2005
2005
Cleavage furrow formation marks the onset of cell division during early anaphase. The small GTPase RhoA and its regulators ECT2… (More)
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2004
2004
The human ECT2 protooncogene encodes a guanine nucleotide exchange factor for the Rho GTPases and regulates cytokinesis. Although… (More)
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Highly Cited
1999
Highly Cited
1999
Animal cells divide into two daughter cells by the formation of an actomyosin-based contractile ring through a process called… (More)
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Highly Cited
1997
Highly Cited
1997
Computer analysis of a conserved domain, BRCT, first described at the carboxyl terminus of the breast cancer protein BRCA1, a p53… (More)
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