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ECO-4601

Known as: TLN-4601 
National Institutes of Health

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2 relations
TLN 4601

Broader (1)

diazepinomicin

Papers overview

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2010
2010
A phase II trial of TLN-4601 in patients with glioblastoma multiforme (GBM) at first progression.
2094 Background: TLN-4601 is a structurally novel farnesylated dibenzodiazepinone that has demonstrated broad in vitro… 
2009
2009
Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand
PURPOSE ECO-4601 is a structurally novel farnesylated dibenzodiazepinone discovered through DECIPHER technology, Thallion's… 
2008
2008
579 POSTER Biological and biochemical activity of TLN-4601 in pancreatic cancer
2007
2007
Phase I pharmacokinetic study of ECO-4601, a novel bifunctional targeting agent
B119 Background: ECO-4601 (U.S. Patent 7,101,872) is a structurally novel farnesylated dibenzodiazepinone with broad µM in vitro… 
2007
2007
ECO-4601 inhibits the Ras MAPK signaling pathway by dislodging Ras from the cell plasma membrane
415 ECO-4601 (MW 462), a farnesylated dibenzodiazepinone, is a structurally novel compound identified using Ecopia’s genomic… 
2006
2006
Pharmacokinetic and ADME studies of the antitumor compound ECO-4601
3094 ECO-4601 (MW 463) is a structurally novel compound discovered using Ecopia’s genomic DECIPHER® technology platform. The in… 
2006
2006
519 POSTER Safety profile of ECO-4601, a novel PBR ligand anticancer agent, in primates
2006
2006
369 POSTER The anticancer agent, ECO-4601, is a potent inhibitor of the Ras-mitogen-activated protein kinase pathway
2005
2005
ECO-4601, a novel anticancer compound, is a peripheral benzodiazepine receptor ligand and induces apoptosis in gliomas
Proc Amer Assoc Cancer Res, Volume 46, 2005 5896 ECO-4601 is a structurally novel farnesylated dibenzodiazepinone (MW 462… 
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