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diazepinomicin
Known as:
11h-dibenzo(B,E)(1,4)diazepin-11-one, 5,10-dihydro-4,6,8-trihydroxy-10-((2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl)-
A potent inhibitor of the RAS/RAF/MAPK signaling pathway with potential antineoplastic activity. Diazepinomicin binds to and inhibits Ras kinase…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (1)
Dibenzazepines
Narrower (2)
ECO-4601
TLN 4601
RAF Proto-Oncogene Serine/Threonine-Protein Kinase, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Antioxidant and Anti-Protease Activities of Diazepinomicin from the Sponge-Associated Micromonospora Strain RV 115
U. Abdelmohsen
,
Matthias Szesny
,
+4 authors
U. Hentschel
2012
Corpus ID: 54721008
Diazepinomicin is a dibenzodiazepine alkaloid with an unusual structure among the known microbial metabolites discovered so far…
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