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E3 SUMO-Protein Ligase PIAS1
Known as:
AR Interacting Protein
, PIAS1
, Gu-Binding Protein
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E3 SUMO-protein ligase PIAS1 (651 aa, ~72 kDa) is encoded by the human PIAS1 gene. This protein is involved in the mediation of protein sumoylation.
National Institutes of Health
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Related topics
Related topics
8 relations
Enzyme Gene
Interferon Signaling Process
Ligase Gene
Nucleoplasm
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Phosphorylation of Protein Inhibitor of Activated STAT1 (PIAS1) by MAPK-Activated Protein Kinase-2 Inhibits Endothelial Inflammation via Increasing Both PIAS1 Transrepression and SUMO E3 Ligase…
K. Heo
,
Eugene B. Chang
,
+6 authors
J. Abe
Arteriosclerosis, Thrombosis and Vascular Biology
2013
Corpus ID: 26496931
Objective—Protein inhibitor of activated signal transducer and activator of transcription-1 (PIAS1) is known to function as small…
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Highly Cited
2012
Highly Cited
2012
Molecular and Cellular Pathobiology The SUMOE 3-ligase PIAS 1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
A. Rabellino
,
Brandon Carter
,
+8 authors
P. Scaglioni
2012
Corpus ID: 17821027
The ubiquitin-like SUMO proteins covalently modify protein substrates and regulate their functional properties. In a broad…
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2012
2012
Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis.
Ping Chen
,
Deshou Zhao
,
Yun-wei Sun
,
Liya Huang
,
Shu-xian Zhang
,
Yao-zong Yuan
Oncology Report
2012
Corpus ID: 13178526
Protein inhibitor of activated STAT-1 (PIAS1) is a novel modulator of the JAK/STAT signaling pathway that negatively…
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2011
2011
mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer.
Jia Wei
,
C. Costa
,
+12 authors
Baorui Liu
Journal of the National Cancer Institute
2011
Corpus ID: 205183600
Breast cancer susceptibility gene 1 (BRCA1) has a central role in chemotherapy-induced DNA damage response. The protein inhibitor…
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2011
2011
SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.
E. Dütting
,
Nadja Schröder-Kress
,
H. Sticht
,
R. Enz
Biochemical Journal
2011
Corpus ID: 25419369
The central nervous system regulates neuronal excitability by macromolecular signalling complexes that consist of functionally…
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2007
2007
Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1α binding to PIAS1
Wei Lun Nien
,
S. Dauphinee
,
Lori D. Moffat
,
C. K. Too
Molecular and Cellular Endocrinology
2007
Corpus ID: 21493250
Highly Cited
2002
Highly Cited
2002
Protein Inhibitors of Activated STAT Resemble Scaffold Attachment Factors and Function as Interacting Nuclear Receptor Coregulators*
Jiann-an Tan
,
S. H. Hall
,
K. G. Hamil
,
G. Grossman
,
P. Petrusz
,
F. S. French
Journal of Biological Chemistry
2002
Corpus ID: 41500369
Protein inhibitor of activated STAT1 (PIAS1) functions as a nuclear receptor coregulator and is expressed in several cell types…
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2001
2001
Induction of Apoptosis by Protein Inhibitor of Activated Stat1 through c-Jun NH2-terminal Kinase Activation*
Bin Liu
,
K. Shuai
Journal of Biological Chemistry
2001
Corpus ID: 39880867
Members of the protein inhibitor of activated signal transducer and activator of transcription (STAT) family (PIAS family) of…
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Highly Cited
2000
Highly Cited
2000
In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium.
T. Kelley
,
H. Elmer
Journal of Clinical Investigation
2000
Corpus ID: 24653787
Inducible nitric oxide synthase-2 (NOS2) expression has been shown to be reduced in cystic fibrosis (CF) epithelial cells…
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Highly Cited
1998
Highly Cited
1998
Beta-galactoside-binding protein (beta GBP) alters the cell cycle, up-regulates expression of the alpha- and beta-chains of the IFN-gamma receptor, and triggers IFN-gamma-mediated apoptosis of…
A. Allione
,
V. Wells
,
G. Forni
,
L. Mallucci
,
F. Novelli
Journal of Immunology
1998
Corpus ID: 3084300
In this paper, the effects of beta-galactoside binding protein (beta GBP), the LGALS1 gene product, on the cell cycle progression…
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