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Immunocytochemical Localization of the GABACReceptor ρ Subunits in the Mammalian Retina
Polyclonal antibodies against the N terminus of the rat ρ1 subunit were generated to study the distribution of GABAC receptors in the mammalian retina. The specificity of the antibodies was tested inExpand
Expression of GABA Receptor ρ1 and ρ2 Subunits in the Retina and Brain of the Rat
We have investigated the distribution of GABA receptor ρ1 and ρ2 subunits in the rat central nervous system. Cloning of rat ρ1 and ρ2 cDNA fragments revealed similarities to the corresponding humanExpand
Synaptic clustering of GABAC receptor ρ‐subunits in the rat retina
Polyclonal antibodies which recognize the ρ‐subunits of the GABAC receptor were applied to sections of the rat retina. Strong punctate immunoreactivity was found in the inner plexiform layer (IPL),Expand
Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins.
The interplay between kinases and phosphatases represents a fundamental regulatory mechanism in biological systems. Being less numerous than kinases, phosphatases increase their diversity by theExpand
GABAC receptor ρ subunits are heterogeneously expressed in the human CNS and form homo‐ and heterooligomers with distinct physical properties
  • R. Enz, G. Cutting
  • Biology, Medicine
  • The European journal of neuroscience
  • 1 January 1999
In the central nervous system, receptors for γ‐aminobutyric acid (GABA) are responsible for inhibitory neurotransmission. Anatomical and electrophysiological studies indicate that GABAC receptors areExpand
The trick of the tail: protein–protein interactions of metabotropic glutamate receptors
  • R. Enz
  • Biology, Medicine
  • BioEssays : news and reviews in molecular…
  • 1 January 2007
It was initially believed that G‐protein‐coupled receptors, such as metabotropic glutamate receptors, could simply be described as individual proteins that are associated with intracellular signalExpand
Expression of GABA receptor rho 1 and rho 2 subunits in the retina and brain of the rat.
We have investigated the distribution of GABA receptor rho 1 and rho 2 subunits in the rat central nervous system. Cloning of rat rho 1 and rho 2 cDNA fragments revealed similarities to theExpand
Expression of the mRNA of Seven Metabotropic Glutamate Receptors (mGluR1 to 7) in the Rat Retina. An In Situ Hybridization Study on Tissue Sections and Isolated Cells
We have studied the expression of mRNAs for seven metabotropic glutamate receptors (mGluR1–7) in the retina of the adult rat by in situ hybridization with tissue sections and isolated cells usingExpand
GABAC Receptors: A Molecular View
  • R. Enz
  • Chemistry, Medicine
  • Biological chemistry
  • 28 January 2001
Abstract In the central nervous system inhibitory neurotransmission is primarily achieved through activation of receptors for γaminobutyric acid (GABA). Three types of GABA receptors have beenExpand
Expression of the Voltage-Gated Chloride Channel ClC-2 in Rod Bipolar Cells of the Rat Retina
Voltage-gated chloride channels (ClC) are highly conserved during evolution and appear to participate in a variety of physiological functions. Recently, ClC-2 was proposed to play a role inExpand
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