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E2F6 gene

Known as: E2F transcription factor 6, E2F-6, E2F Transcription Factor 6 Gene 
This gene is involved in cell cycle entry.
National Institutes of Health

Related topics

Related topics

4 relations
Homo sapiensTranscriptional RegulationTranscriptional Repressiondna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Comprehensive Analysis of the Expression and Prognosis for E2Fs in Human Breast Cancer.
Highly Cited
2018
Highly Cited
2018
L3MBTL2 orchestrates ubiquitin signaling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
Cells respond to cytotoxic DNA double-strand breaks (DSBs) by recruiting DNA repair proteins to the damaged site. This… 
Highly Cited
2014
Highly Cited
2014
miR-185 Suppresses Tumor Proliferation by Directly Targeting E2F6 and DNMT1 and Indirectly Upregulating BRCA1 in Triple-Negative Breast Cancer
Breast cancer is a major public health problem all over the world, and the current treatment strategies are not potent enough for… 
Review
2014
Review
2014
Promising roles of mammalian E2Fs in hepatocellular carcinoma.
Highly Cited
2011
Highly Cited
2011
Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression
We show that the centrosome‐ and microtubule‐regulating protein γ‐tubulin interacts with E2 promoter binding factors (E2Fs) to… 
Highly Cited
2010
Highly Cited
2010
miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets.
BCR-ABL negative myeloproliferative neoplasms (MPNs; polycythemia vera, essential thrombocythemia, primary myelofibrosis) are… 
Highly Cited
2005
Highly Cited
2005
Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers
SummaryFamilial breast cancers that are associated with BRCA1 or BRCA2 germline mutations differ in both their morphological and… 
Highly Cited
2003
Highly Cited
2003
E2F6 Negatively Regulates BRCA1 in Human Cancer Cells without Methylation of Histone H3 on Lysine 9*
E2F6 contains a DNA binding domain that is very similar to that of the other members of the E2F family of transcriptional… 
Highly Cited
2003
Highly Cited
2003
Dynamic Recruitment of NF-Y and Histone Acetyltransferases on Cell-cycle Promoters*
Regulation of transcription during the cell-cycle is under the control of E2 factors (E2Fs), often in cooperation with nuclear… 
Highly Cited
2001
Highly Cited
2001
p19ARF targets certain E2F species for degradation
p19ARF suppresses the growth of cells lacking p53 through an unknown mechanism. p19ARF was found to complex with transcription… 
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