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E 4177

Known as: E-4177, E4177 
National Institutes of Health

Papers overview

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2005
2005
Recent studies have shown that angiotensin II type 1 (AT1) receptor-mediated Akt activation induces vascular smooth muscle cell… Expand
2004
2004
Abstract—Although the angiotensin-converting enzyme (ACE) inhibitor-induced bradykinin enhances nitric oxide (NO) release… Expand
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Highly Cited
1999
Highly Cited
1999
The Dahl salt-sensitive (DS) rat, a genetic model of salt-induced hypertension in humans, is more likely to develop severe… Expand
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1999
1999
The present study examined the role of intrarenal bradykinin in angiotensin-converting enzyme inhibitor (ACEI)-induced dilation… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The effect of balloon injury on the arterial signal transduction pathway has not been examined. In vitro studies show… Expand
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Highly Cited
1998
Highly Cited
1998
Because hepatocyte growth factor (HGF) is a member of the endothelium-specific growth factors, we hypothesized that HGF may play… Expand
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1997
1997
Using Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a new model of human non-insulin-dependent diabetes mellitus (NIDDM), we… Expand
1997
1997
Changes in the mRNA levels for aldosterone synthase cytochrome P450 (CYP11B2 or P450aldo) and 11 beta hydroxylase cytochrome P450… Expand
Highly Cited
1996
Highly Cited
1996
The efficacy of angiotensin converting enzyme (ACE) inhibitors is well known to prevent the formation of angiotensin II (Ang II… Expand
1993
1993
E4177, 3-[(2'-carboxybiphenyl-4-yl)methyl]-2-cyclopropyl-7-methyl-3H- imidazo[4,5-b]pyridine, was characterized by in vitro… Expand