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Drug Screening Assays, Antitumor

Known as: Cancer Drug Tests, Antitumor Drug Screening Assay, Drug Test, Cancer 
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and… 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
PurposeThe primary objective of this study is to evaluate the safety, tolerance, and pharmacokinetic profile of liver-directed… 
Review
2012
Review
2012
To assess the feasibility of using sandwich-cultured human hepatocytes (SCHHs) as a model to characterize transport kinetics for… 
Review
2005
Review
2005
Cell-based in vitro models are invaluable tools in elucidating the pharmacokinetic profile of a drug candidate during its drug… 
Review
2002
Review
2002
The pharmacological effects of a drug are highly dependent on the absorption, metabolism, elimination, and distribution of the… 
Highly Cited
1989
Highly Cited
1989
Chinese hamster ovary cells (HA1) were exposed to therapeutic ultrasound (F = 2.025 MHz) in the presence of various drugs at… 
Review
1985
Review
1985
The potential for the use of microorganisms as tools in the study of drug metabolism appears to be unlimited. The selected… 
Highly Cited
1982
Highly Cited
1982
This study reports on the development of drug containing acrylic strips for delivering antimicrobial agents and compares the in… 
Highly Cited
1979
Highly Cited
1979
The benzodiazepines are potent anticonvulsants for a wide variety of experimental and clinical seizure disorders1,2. The… 
Highly Cited
1978
Highly Cited
1978
The ultrastructure of primary hepatocytes cultured for 2 to 17 days on floating collagen membrane was evaluated. A pellet of the…