Droxidopa

Known as: DL-threo-3,4-Dihydroxyphenylserine, 3,4-threo-DOPS, threo DOPS 
A precursor of noradrenaline that is used in the treatment of parkinsonism. The racemic form (DL-threo-3,4-dihydroxyphenylserine) has also been used… (More)
National Institutes of Health

Papers overview

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2015
2015
Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from… (More)
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Highly Cited
2014
Highly Cited
2014
OBJECTIVE To determine whether droxidopa, an oral norepinephrine precursor, improves symptomatic neurogenic orthostatic… (More)
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Highly Cited
2010
Highly Cited
2010
Locus ceruleus (LC)-supplied norepinephrine (NE) suppresses neuroinflammation in the brain. To elucidate the effect of LC… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES To evaluate the reliability and feasibility of assessing the performance of medical specialist registrars (SpRs) using… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine-1-phosphate (SPP) has diverse biological functions acting inside cells as a second messenger to regulate… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND We previously reported that N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) treatment caused large increases of… (More)
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Highly Cited
1998
Highly Cited
1998
Mice lacking the hypoxia-inducible transcription factor EPAS1 die at mid-gestation. Despite normal morphological development of… (More)
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Highly Cited
1998
Highly Cited
1998
Sphingosine-1-phosphate (SPP) is a novel lipid messenger that has dual function. Intracellularly it regulates proliferation and… (More)
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Highly Cited
1993
Highly Cited
1993
Ceramide activates a cytosolic protein phosphatase present in rat T9 glioma cells and rat brain. Ceramide-activated protein… (More)
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Highly Cited
1990
Highly Cited
1990
Vascular anticoagulant alpha (VAC alpha, annexin V) is a member of the family of calcium and phospholipid binding proteins, the… (More)
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