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Down-Regulation

Known as: Down Regulation, Down-Regulation (Physiology), Downregulation 
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
MYC contributes to the pathogenesis of a majority of human cancers, yet strategies to modulate the function of the c-Myc… Expand
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Highly Cited
2004
Highly Cited
2004
We describe here a multiplexed protein quantitation strategy that provides relative and absolute measurements of proteins in… Expand
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Highly Cited
2004
Highly Cited
2004
The present report meta-analyzes more than 300 empirical articles describing a relationship between psychological stress and… Expand
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Highly Cited
2004
Highly Cited
2004
CD4+CD25+ regulatory cells are a subpopulation of T lymphocytes of thymic origin. However, recent data suggest an alternative… Expand
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Review
2002
Review
2002
  • E. Shevach
  • Nature Reviews Immunology
  • 2002
  • Corpus ID: 351718
Several mechanisms control discrimination between self and non-self, including the thymic deletion of autoreactive T cells and… Expand
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Highly Cited
2000
Highly Cited
2000
The Snail family of transcription factors has previously been implicated in the differentiation of epithelial cells into… Expand
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Highly Cited
2000
Highly Cited
2000
Monocytes/macrophages exposed to LPS show reduced responses to second stimulation with LPS, which is termed LPS tolerance. In… Expand
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Review
1999
Review
1999
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was identified in terms of its cDNA sequence… Expand
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Highly Cited
1995
Highly Cited
1995
We have previously demonstrated that human peripheral blood low density mononuclear cells cultured in granulocyte/macrophage… Expand
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Highly Cited
1993
Highly Cited
1993
CONGENERS of nitrogen monoxide (NO) are neuroprotective and neurodestructive1– 7. To address this apparent paradox, we considered… Expand