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Dihydroorotase
Known as:
Dehydrase, Carbamoylaspartic
, (S)-Dihydroorotate amidohydrolase
, Amidohydrolase, Dihydro-Orotate
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An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro…
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National Institutes of Health
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Related topics
Related topics
8 relations
Narrower (1)
CAD trifunctional enzyme
In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Microcalorimetry of interaction of dihydro-imidazo-phenanthridinium (DIP)-based compounds with duplex DNA.
Kevin M. Guthrie
,
Alexis D. C. Parenty
,
Louise V. Smith
,
L. Cronin
,
A. Cooper
Biophysical Chemistry
2007
Corpus ID: 11127876
Highly Cited
2006
Highly Cited
2006
Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides.
M. Curado
,
Carolina B. A. Oliveira
,
J. G. Jesús
,
S. C. Santos
,
J. Seraphin
,
P. H. Ferri
Phytochemistry
2006
Corpus ID: 27284232
Highly Cited
2002
Highly Cited
2002
Barbiturase, a Novel Zinc-containing Amidohydrolase Involved in Oxidative Pyrimidine Metabolism*
C. Soong
,
J. Ogawa
,
E. Sakuradani
,
S. Shimizu
Journal of Biological Chemistry
2002
Corpus ID: 26415398
Barbiturase, which catalyzes the reversible amidohydrolysis of barbituric acid to ureidomalonic acid in the second step of…
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1995
1995
Function of conserved histidine residues in mammalian dihydroorotase.
B. Zimmermann
,
N. Kemling
,
D. R. Evans
Biochemistry
1995
Corpus ID: 43537381
Dihydroorotase (DHOase, EC 3.5.2.3) catalyzes the reversible cyclization of carbamyl aspartate to form dihydroorotate, the third…
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1989
1989
The presence of amplified regions affects the stability of chromosomes in drug-resistant Chinese hamster cells.
M. Miele
,
S. Bonatti
,
P. Menichini
,
L. Ottaggio
,
Angelo Abbondandolo
Mutation research
1989
Corpus ID: 33602596
Highly Cited
1981
Highly Cited
1981
The enzymes of pyrimidine biosynthesis in a range of parasitic protozoa and helminths.
B. Hill
,
J. Kilsby
,
G. Rogerson
,
R. McIntosh
,
C. Ginger
Molecular and biochemical parasitology (Print)
1981
Corpus ID: 28788860
1979
1979
Inhibition of synthesis of pyrimidine nucleotides by 2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone.
L. Bennett
,
D. Smithers
,
L. Rose
,
D. J. Adamson
,
H. Thomas
Cancer Research
1979
Corpus ID: 40976085
Abstract Dichloroallyl lawsone [2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone, NSC 126771] is of interest as an antitumor…
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Highly Cited
1976
Highly Cited
1976
Stable mutants of mammalian cells that overproduce the first three enzymes of pyrimidine nucleotide biosynthesis
T. D. Kempe
,
E. A. Swyryd
,
M. Bruist
,
G. Stark
Cell
1976
Corpus ID: 617090
1976
1976
Regulation of arginine and pyrimidine biosynthesis in Pseudomonas putida.
S. Condon
,
J. Collins
,
G. O'donovan
Journal of General Microbiology
1976
Corpus ID: 28103474
Repression of biosynthetic enzyme synthesis in Pseudomonas putida is incomplete even when the bacteria are growing in a…
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1971
1971
Antimicrobial properties of natural phenols and related compounds.
L. Jurd
,
A. King
,
K. Mihara
,
W. Stanley
Applied microbiology
1971
Corpus ID: 6030963
Obtusastyrene (4-cinnamylphenol) displays effective antimicrobial activity in vitro against a variety of gram-positive bacteria…
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