Dihydroorotase

Known as: Dehydrase, Carbamoylaspartic, (S)-Dihydroorotate amidohydrolase, Amidohydrolase, Dihydro-Orotate 
An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
A new form of metabolic flux analysis (MFA) called thermodynamics-based metabolic flux analysis (TMFA) is introduced with the… (More)
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2004
2004
Dihydroorotase (DHO) is a zinc metalloenzyme that functions in the pathway for the biosynthesis of pyrimidine nucleotides by… (More)
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Highly Cited
2004
Highly Cited
2004
The protein phosphatases1 (PP1) and 2A (PP2A) serve as ceramide-activated protein phosphatases (CAPP). In this study, the… (More)
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Highly Cited
2003
Highly Cited
2003
Sphingosine-1-phosphate (S1P) is a highly bioactive lipid that exerts numerous biological effects both intracellularly as a… (More)
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Highly Cited
2002
Highly Cited
2002
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biological processes by binding to a… (More)
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2001
2001
Dihydroorotase plays a key role in pyrimidine biosynthesis by catalyzing the reversible interconversion of carbamoyl aspartate to… (More)
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Highly Cited
1999
Highly Cited
1999
Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a wide range of antimicrobial agents… (More)
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1998
1998
Of several furanocoumarins [5-methoxypsoralen (5-MOP), 8-methoxypsoralen (8-MOP), 5-hydroxypsoralen (5-OH-P), 8-hydroxypsoralen… (More)
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Highly Cited
1996
Highly Cited
1996
The M protein has been postulated to be a major group A streptococcal (GAS) virulence factor because of its contribution to the… (More)
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1992
1992
Dihydroorotase and dihydroorotate dehydrogenase, two enzymes of the pyrimidine biosynthetic pathway, were purified from… (More)
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