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Configurable 3D-Printed millifluidic and microfluidic 'lab on a chip' reactionware devices.
- Philip J. Kitson, Mali H Rosnes, Victor Sans, Vincenza Dragone, L. Cronin
- Chemistry, Materials ScienceLab on a Chip
- 14 August 2012
We utilise 3D design and 3D printing techniques to fabricate a number of miniaturised fluidic 'reactionware' devices for chemical syntheses in just a few hours, using inexpensive materials producing…
3D printing of versatile reactionware for chemical synthesis
- Philip J. Kitson, S. Glatzel, Wei Chen, Chang-Gen Lin, Yu-Fei Song, L. Cronin
- Materials ScienceNature Protocols
- 1 May 2016
A general approach for the production of bespoke chemical reactors, termed reactionware, using two different approaches to extrusion-based 3D printing, which allows versatility in the design and use of reactionware based on the specific needs of the experimental user.
Exoplanet Biosignatures: Future Directions
A Bayesian method for guiding future directions for detection of life on exoplanets is introduced and examples for how the Bayesian formalism could guide future search strategies are provided.
Decoupled catalytic hydrogen evolution from a molecular metal oxide redox mediator in water splitting
A platinum-catalyzed system can produce pure hydrogen over 30 times faster than state-of-the-art proton exchange membrane electrolyzers at equivalent platinum loading, and essentially eliminates the hazardous issue of product gas crossover at the low current densities that characterize renewables-driven water-splitting devices.
Integrated 3D-printed reactionware for chemical synthesis and analysis.
Using a low-cost 3D printer and open-source design software, reactionware for organic and inorganic synthesis was produced, which included printed- in catalysts and other architectures with printed-in components for electrochemical and spectroscopic analysis.
Decoupling hydrogen and oxygen evolution during electrolytic water splitting using an electron-coupled-proton buffer.
The concept of the electron-coupled-proton buffer (ECPB) is introduced, whereby O⁂ and H₂ can be produced at separate times during water electrolysis, which could have advantages in preventing gas mixing in the headspaces of high-pressure electrolysis cells, with implications for safety and electrolyser degradation.
Controlling an organic synthesis robot with machine learning to search for new reactivity
An organic synthesis robot is presented that can perform chemical reactions and analysis faster than they can be performed manually, as well as predict the reactivity of possible reagent combinations after conducting a small number of experiments, thus effectively navigating chemical reaction space.
Organic synthesis in a modular robotic system driven by a chemical programming language
An autonomous compiler and robotic laboratory platform to synthesize organic compounds on the basis of standardized methods descriptions, and a program, the Chempiler, to produce specific, low-level instructions for modular hardware of the laboratory-scale synthesis robot.
Using Evolutionary Algorithms and Machine Learning to Explore Sequence Space for the Discovery of Antimicrobial Peptides