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Diamidine

 
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Protein arginine methylation is a posttranslational modification critical for a variety of biological processes. Misregulation of… Expand
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Highly Cited
2007
Highly Cited
2007
Treatment of many infectious diseases is under threat from drug resistance. Understanding the mechanisms of resistance is as high… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT The aromatic diamidine pentamidine has long been used to treat early-stage human African trypanosomiasis (HAT). Two… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Resistance to diminazene aceturate (Berenil) is a severe problem in the control of African trypanosomiasis in domestic… Expand
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Highly Cited
2004
Highly Cited
2004
The DNA minor groove is the interaction site for many enzymes and transcription control proteins and as a result, development of… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT Sleeping sickness, caused by Trypanosoma brucei spp., has become resurgent in sub-Saharan Africa. Moreover, there is an… Expand
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Review
1999
Review
1999
Resistance to currently used drugs is a serious problem in most fields of antimicrobial chemotherapy. Crossresistance between two… Expand
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Highly Cited
1995
Highly Cited
1995
The African trypanosome, Trypanosoma brucei brucei, possesses at least two nucleoside transporter systems designated P1 and P2… Expand
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Highly Cited
1995
Highly Cited
1995
Following the demonstration that the transport of melaminophenyl arsenical drugs in Trypanosoma brucei is dependent upon an… Expand
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Highly Cited
1983
Highly Cited
1983
  • T. K. Jha
  • Transactions of the Royal Society of Tropical…
  • 1983
  • Corpus ID: 36358616
Pentamidine isethionate was found to be a very effective therapeutic agent in the treatment of pentavalent antimonial-resistant… Expand
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