Desmosterol

Known as: Desmosterol [Chemical/Ingredient], Demosterol, 24 Dehydrocholesterol 
An intermediate in the synthesis of cholesterol.
National Institutes of Health

Papers overview

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2013
2013
UNLABELLED Dysregulation of the cholesterol synthesis pathway and accumulation of cholesterol in the liver are linked to the… (More)
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Highly Cited
2012
Highly Cited
2012
Inflammation and macrophage foam cells are characteristic features of atherosclerotic lesions, but the mechanisms linking… (More)
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Highly Cited
2008
Highly Cited
2008
Transporters in the ABCG family appear to be involved in the cellular excretion of cholesterol and other sterols in a cell- and… (More)
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2006
2006
Desmosterol is an immediate precursor of cholesterol in the Bloch pathway of sterol synthesis and an abundant membrane lipid in… (More)
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Highly Cited
2006
Highly Cited
2006
The liver X receptors (LXRs) are ligand-activated transcription factors that regulate the expression of genes controlling lipid… (More)
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2005
2005
Recently, knockout mice entirely lacking cholesterol have been described as showing only a mild phenotype. For these animals… (More)
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2002
Highly Cited
2002
In patients with the inherited disease of phytosterolemia, elevated concentrations of plant sterols (eg, campesterol and… (More)
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1998
1998
Previously we demonstrated high concentrations of desmosterol and docosahexaenoic acid (DHA, 22:6 n-3) in monkey testes and sperm… (More)
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1993
1993
Spermatozoa represent a tissue readily accessible for study after various exogenous perturbations. To characterize the lipid… (More)
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Highly Cited
1990
Highly Cited
1990
To investigate the regulation of serum levels of cholesterol precursor sterols and plant sterols, these noncholesterol sterols… (More)
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