Defective Viruses

Known as: Virus, Defective Interfering, Defective Virus, Viruses, Defective 
Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
To realize the therapeutic potential of RNA drugs, efficient, tissue-specific and nonimmunogenic delivery technologies must be… (More)
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Highly Cited
2003
Highly Cited
2003
Viral replication usually requires that innate intracellular lines of defence be overcome, a task usually accomplished by… (More)
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Highly Cited
2003
Highly Cited
2003
Double-stranded short interfering RNAs (siRNA) induce post-transcriptional silencing in a variety of biological systems. In the… (More)
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Highly Cited
2003
Highly Cited
2003
The Arabidopsis genome encodes four Dicer-like (DCL) proteins, two of which contain putative nuclear localization signals. This… (More)
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Highly Cited
2002
Highly Cited
2002
Chemically synthesised 21-23 bp double-stranded short interfering RNAs (siRNA) can induce sequence-specific post-transcriptional… (More)
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Highly Cited
2002
Highly Cited
2002
Post-transcriptional gene silencing (PTGS) is a sequence-specific degradation mechanism that operates in almost all eukaryotic… (More)
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Review
1996
Review
1996
MHC class I molecules predominantly bind to peptides derived from a cytosolic pool of polypeptides. Little is known about the… (More)
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Highly Cited
1996
Highly Cited
1996
Adult T-cell leukemia (ATL), an aggressive neoplasm of mature helper T cells, is etiologically linked with human T lymphotropic… (More)
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Review
1991
Review
1991
DI viruses and defective viruses generally are widespread in nature. Laboratory studies show that they can sometimes exert… (More)
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Highly Cited
1987
Highly Cited
1987
These experiments identify an Epstein-Barr virus-encoded gene product, called ZEBRA (BamHI fragment Z Epstein-Barr replication… (More)
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