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Daunorubicin Hydrochloride

Known as: 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride, Daunomycin-HCL, Daunorubicin.HCl 
The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits… 
National Institutes of Health

Related topics

Related topics

30 relations
AnthracyclinesCongestive heart failureCytarabine-Daunorubicin RegimenDATOP protocol

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CerubidineDaunoblastin

Papers overview

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2010
2010
Differences in accumulation of anthracyclines daunorubicin, doxorubicin and epirubicin in rat tissues revealed by immunocytochemistry
Although anthracycline antibiotics daunorubicin (DR), doxorubicin (DX), and epirubicin (ER) possess minor differences in their… 
2009
2009
Specific interaction of 4'-O-(a-l-Cladinosyl) daunorubicin with human serum albumin: The binding site II on HSA molecular using spectroscopy and modeling.
2003
2003
The Use of Cardiac Biomarkers to Detect Myocardial Damage Induced by Chemotherapeutic Agents
The treatment of neoplastic diseases with chemotherapeutic agents was initiated more than 50 yr ago. Since then, antineoplastic… 
2000
2000
Liposomal daunorubicin plasmatic and renal disposition in patients with acute leukemia
Abstract Liposomal formulations of anthracyclines have been developed to increase their delivery to solid tumors while reducing… 
Highly Cited
1995
Highly Cited
1995
Phase I trial of high-dose tamoxifen as a modulator of drug resistance in combination with daunorubicin in patients with relapsed or refractory acute leukemia.
Tamoxifen and its main metabolite N-desmethyltamoxifen (NDMTmx) have been shown to increase intracellular daunorubicin (DNR… 
1994
1994
Effects of an intravitreal daunomycin implant on experimental proliferative vitreoretinopathy: simultaneous pharmacokinetic and pharmacodynamic evaluations.
Intravitreal daunomycin (D) effectively suppresses cellular proliferation in experimental proliferative vitreoretinopathy (PVR… 
1981
1981
Interactions of daunomycin and melanotropin–daunomycin with DNA
The specific recognition of fluorescein–melanotropin and melanotropin–ferritin–fluorescein conjugates by melanotropin (MSH… 
Highly Cited
1980
Highly Cited
1980
Cytofluorescence localization of anthracycline antibiotics.
Previous fluorescence microscopic studies have shown daunorubicin (DNR) and Adriamycin (ADR) are localized in cell nuclei… 
1977
1977
Differential sensitivity of Xeroderma pigmentosum cells of different repair capacities towards the chromosome breaking action of carcinogens and mutagens
The sensitivity of cultured fibroblasts obtained from four unrelated Xeroderma pigmentosum patients (XP‐K, XP‐C, XP‐E and XP‐H… 
1977
1977
Thermodynamics of the interaction of daunomycin with DNA.
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