Daunorubicin Hydrochloride

Known as: 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride, Daunomycin-HCL, Daunorubicin.HCl 
The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits… (More)
National Institutes of Health

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AnthracyclinesCongestive heart failureCytarabine-Daunorubicin RegimenDATOP protocol
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CerubidineDaunoblastin

Papers overview

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2015
2015
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells.
Nucleophosmin (NPM1) mutations represent an attractive therapeutic target in acute myeloid leukemia (AML) because they are common… (More)
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Highly Cited
2003
Highly Cited
2003
A feasibility study of simultaneous administration of gemtuzumab ozogamicin with intensive chemotherapy in induction and consolidation in younger patients with acute myeloid leukemia.
The feasibility of combining gemtuzumab ozogamicin (GO) with intensive chemotherapy as first-line treatment of acute myeloid… (More)
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2002
2002
Formulation and in vivo evaluation of niosome-encapsulated daunorubicin hydrochloride.
The central aim of this present study was to modify the reverse evaporation process, such that an enhanced entrapment, with… (More)
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2000
2000
Long-term follow-up confirms the benefit of all-trans retinoic acid in acute promyelocytic leukemia
First results of a randomized trial (APL91 trial) and other randomized or non-randomized studies have shown that ATRA followed by… (More)
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2000
2000
Long-term follow-up confirms the benefit of all-trans retinoic acid in acute promyelocytic leukemia. European APL group.
First results of a randomized trial (APL91 trial) and other randomized or non-randomized studies have shown that ATRA followed by… (More)
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Highly Cited
1998
Highly Cited
1998
Adjunctive daunorubicin in the treatment of proliferative vitreoretinopathy: results of a multicenter clinical trial. Daunomycin Study Group.
PURPOSE To assess the efficacy and safety of adjunctive daunorubicin during vitrectomy surgery in eyes with idiopathic… (More)
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1998
1998
TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60.
Costimulation of TNFR80 can strongly enhance TNFR60-induced cell death. In this study, we show that this enhancement is TNFR60… (More)
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Highly Cited
1997
Highly Cited
1997
Acute Myeloid Leukemia in the Elderly : Assessment of Multidrug Resistance ( MDR 1 ) and Cytogenetics Distinguishes Biologic Subgroups With Remarkably Distinct Responses to Standard Chemotherapy
Compared with younger patients, elderly patients with MDR1 (P ! .0041) were each significantly and independently acute myeloid… (More)
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1997
1997
Use of recombinant granulocyte-macrophage colony-stimulating factor during and after remission induction chemotherapy in patients aged 61 years and older with acute myeloid leukemia (AML)
We conducted a prospective randomized multicenter clinical patients. The median time of recovery of neutrophils totrial comparing… (More)
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1995
1995
Photoprotection of daunorubicin hydrochloride with sodium sulfite.
Protection of 10(-4) M daunorubicin hydrochloride (DNRUB) solutions against photolytic degradation was investigated using sodium… (More)
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