DYRK1A wt Allele

Known as: HP86, Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 1A wt Allele, DYRK 
Human DYRK1A wild-type allele is located in the vicinity of 21q22.13 and is approximately 148 kb in length. This allele, which encodes dual… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
024619962017

Papers overview

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2012
2012
An optimal culture system for human pluripotent stem cells should be fully defined and free of animal components. To date, most… (More)
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2009
2009
NFAT transcription factors are highly phosphorylated proteins residing in the cytoplasm of resting cells. Upon dephosphorylation… (More)
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Highly Cited
2007
Highly Cited
2007
Abnormally high constitutive activity of protein kinase CK2, levels of which are elevated in a variety of tumours, is suspected… (More)
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2007
2007
A 4.3 Mb duplication of chromosome 21 bands q22.13-q22.2 was diagnosed by interphase fluorescent in-situ hybridisation (FISH) in… (More)
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2005
2005
Dual specific protein kinase Dyrks are thought to play a key role in the regulation of cell growth in a variety of cellular… (More)
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Highly Cited
2002
Highly Cited
2002
To investigate the cellular role of dual specificity Yak1-related kinase (Dyrk) 1, a nuclear localized dual specificity protein… (More)
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Highly Cited
2001
Highly Cited
2001
Dyrk is a dual specific protein kinase thought to be involved in normal embryo neurogenesis and brain development. Defects… (More)
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Highly Cited
1999
Highly Cited
1999
The human homologue (MNBH/DYRK1) of the Drosophila minibrain gene maps to human chromosome 21 within the Down syndrome (DS… (More)
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1997
1997
We mapped the murine copy of the Dyrk gene and examined its subcellular localization and self-interaction. We found that: (1… (More)
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Highly Cited
1996
Highly Cited
1996
The presence of an extra copy of human chromosome 21 (trisomy 21), especially region 21q22.2, causes many phenotypes in Down… (More)
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