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Tyrosine Phosphorylation

Tyrosine phosphorylation involves the introduction of a phosphoryl group into a compound through the formation of an ester bond between a tyrosine… 
National Institutes of Health

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AXL geneAXL wt AlleleAngiopoietin-1 Receptor, HumanBTK gene

Papers overview

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Highly Cited
2007
Highly Cited
2007
Activation of SHP2 Protein-tyrosine Phosphatase Increases HoxA10-induced Repression of the Genes Encoding gp91PHOX and p67PHOX*
The CYBB and NCF2 genes encode the phagocyte oxidase proteins gp91PHOX and p67PHOX, respectively. These genes are transcribed… 
1995
1995
Integrin signaling: roles for the cytoplasmic tails of αIIbβ3 in the tyrosine phosphorylation of pp125 FAK
pp125FAK (focal adhesion kinase) a protein tyrosine kinase that may mediate cellular responses to adhesion, is activated and… 
1994
1994
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
Nature 372, 186-190(1994) THE contents list in this (the 10 November) issue included a typographical error. 
Highly Cited
1994
Highly Cited
1994
Distinct structural compartmentalization of the signal transducing functions of major histocompatibility complex class II (Ia) molecules
Class II major histocompatibility complex encoded proteins (MHC class II or Ia molecules) are principal plasma membrane proteins… 
Highly Cited
1991
Highly Cited
1991
Surface immunoglobulin crosslinking activates a tyrosine kinase pathway in B cells that is independent of protein kinase C.
It has been found that the principal biochemical pathway activated in B cells stimulated by antigen- or anti-immunoglobulin… 
1990
1990
Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation.
To elucidate the rapid events in signal transduction of human granulocyte-macrophage colony-stimulating factor (GM-CSF) and… 
Highly Cited
1987
Highly Cited
1987
Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.
It is speculated that the transmission of an insulin signal across the plasma membrane of cells occurs through activation of the… 
1986
1986
Protein tyrosine phosphorylation in the cell cycle of BALB/c 3T3 fibroblasts.
Cell cycle-dependent regulation of protein tyrosine phosphorylation in normal BALB/c 3T3 fibroblasts was examined by… 
Highly Cited
1986
Highly Cited
1986
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v…
We provide direct evidence that serine 17 is the major site of serine phosphorylation in p60v-src, the transforming protein of… 
1984
1984
Synthetic peptide substrates for the membrane tyrosine protein kinase stimulated by epidermal growth factor.
The substrate specificity of the epidermal-growth-factor-stimulated tyrosine protein kinase of A431 cell membranes has been…