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Sonic Hedgehog Pathway

Known as: Sonic Hedgehog (Shh) Pathway 
Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) and Desert Hedgehog (Dhh), that play distinct and… Expand
National Institutes of Health

Papers overview

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2017
2017
Background and Purpose— Because of the limitation in treatment window of the r-tPA (recombinant tissue-type plasminogen activator… Expand
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Highly Cited
2013
Highly Cited
2013
The primary cilium is required for Sonic hedgehog (Shh) signaling in vertebrates. In contrast to mutants affecting ciliary… Expand
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Highly Cited
2013
Highly Cited
2013
Bone marrow stromal cells (MSCs) improve neurologic recovery after middle cerebral artery occlusion (MCAo). To examine whether in… Expand
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Highly Cited
2012
Highly Cited
2012
Activation of the sonic hedgehog (SHh) pathway is required for the growth of numerous tissues and organs and recent evidence… Expand
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Highly Cited
2012
Highly Cited
2012
Sulforaphane (SFN), a component of dietary cruciferous vegetables has been characterized for its anti-proliferative properties… Expand
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Highly Cited
2010
Highly Cited
2010
Medulloblastoma encompasses a collection of clinically and molecularly diverse tumour subtypes that together comprise the most… Expand
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2010
2010
Medulloblastoma (MB) represents approximately 4% of adult brain tumours, and as such is a poorly studied disease. Although many… Expand
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2007
2007
A subgroup of medulloblastomas shows constitutive activation of the Sonic hedgehog pathway with expression of GLI1. We identified… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Basal cell carcinoma (BCC) of the skin is the most common human cancer. The genetic alterations underlying BCC… Expand
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Review
2000
Review
2000
The hedgehog signalling pathway has been implicated in many different processes in fly and vertebrate development. It is now… Expand
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