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GLI2 protein, human

Known as: THP2 protein, human, Tax helper protein 2, human, TRE-binding protein 2, human 
Zinc finger protein GLI2 (1586 aa, ~168 kDa) is encoded by the human GLI2 gene. This protein plays a role in embryonic development and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The transforming growth factor-beta (TGF-beta) pathway, which has both tumor suppressor and pro-oncogenic activities… Expand
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Highly Cited
2007
Highly Cited
2007
Hedgehog (Hh) and transforming growth factor-beta (TGF-beta) family members are involved in numerous overlapping processes during… Expand
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Highly Cited
2006
Highly Cited
2006
Gli2 and Gli3 are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse. Gli3 mainly acts as a… Expand
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Highly Cited
2005
Highly Cited
2005
Zinc finger-containing Gli proteins mediate responsiveness to Hedgehog (Hh) signaling, with Gli2 acting as the major… Expand
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Highly Cited
2003
Highly Cited
2003
Sonic hedgehog (Shh) signaling plays a critical role in hair follicle development and skin cancer, but how it controls these… Expand
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Highly Cited
2001
Highly Cited
2001
In mice, three Gli genes are thought to mediate sonic hedgehog (Shh) signaling collectively. Mis-expression studies and analysis… Expand
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Highly Cited
1999
Highly Cited
1999
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… Expand
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Highly Cited
1998
Highly Cited
1998
Foregut malformations (oesophageal atresia, tracheo-oesophageal fistula, lung anomalies and congenital stenosis of the oesophagus… Expand
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Highly Cited
1998
Highly Cited
1998
The expression of genes involved in the Sonic Hedgehog signalling pathway, including Shh, Ptc, Smo, Gli1, Gli2 and Gli3, were… Expand
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Highly Cited
1997
Highly Cited
1997
The correct patterning of vertebrate skeletal elements is controlled by inductive interactions. Two vertebrate hedgehog proteins… Expand
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