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GLI2 protein, human

Known as: THP2 protein, human, Tax helper protein 2, human, TRE-binding protein 2, human 
Zinc finger protein GLI2 (1586 aa, ~168 kDa) is encoded by the human GLI2 gene. This protein plays a role in embryonic development and… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Gli proteins are transcriptional effectors of the Hedgehog signaling pathway. They play key roles in the development of many… Expand
Highly Cited
2006
Highly Cited
2006
ABSTRACT Gli2 and Gli3 are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse. Gli3 mainly… Expand
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Highly Cited
2006
Highly Cited
2006
Hedgehogs (Hhs) are key signaling regulators of stem cell maintenance and tissue patterning in embryos, and activating mutations… Expand
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Highly Cited
2004
Highly Cited
2004
An important question is how the gradient of Hedgehog is interpreted by cells at the level of the Gli transcription factors. The… Expand
Highly Cited
2003
Highly Cited
2003
Sonic hedgehog (Shh) directs the development of ventral cell fates, including floor plate and V3 interneurons, in the mouse… Expand
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Highly Cited
2001
Highly Cited
2001
In mice, three Gli genes are thought to mediate sonic hedgehog (Shh) signaling collectively. Mis-expression studies and analysis… Expand
Highly Cited
1999
Highly Cited
1999
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… Expand
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Highly Cited
1998
Highly Cited
1998
The expression of genes involved in the Sonic Hedgehog signalling pathway, including Shh, Ptc, Smo, Gli1, Gli2 and Gli3, were… Expand
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Highly Cited
1998
Highly Cited
1998
Foregut malformations (oesophageal atresia, tracheo-oesophageal fistula, lung anomalies and congenital stenosis of the oesophagus… Expand
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Highly Cited
1997
Highly Cited
1997
The correct patterning of vertebrate skeletal elements is controlled by inductive interactions. Two vertebrate hedgehog proteins… Expand
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