GLI2 protein, human

Known as: THP2 protein, human, Tax helper protein 2, human, TRE-binding protein 2, human 
Zinc finger protein GLI2 (1586 aa, ~168 kDa) is encoded by the human GLI2 gene. This protein plays a role in embryonic development and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
051020022018

Papers overview

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2014
2014
Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to… (More)
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2011
2011
The Hedgehog pathway functions as an organizer in embryonic development. Aberrant activation of the Hedgehog pathway has been… (More)
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2011
2011
Aberrant activation of HH/GLI has recently been reported in multiple cancer types, yet its role in oral squamous cell carcinoma… (More)
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2010
2010
BACKGROUND The transforming growth factor-beta (TGF-beta) pathway, which has both tumor suppressor and pro-oncogenic activities… (More)
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2009
2009
GLI2 (GLI-Kruppel family member 2), a zinc finger transcription factor that mediates Hedgehog signaling, is implicated in the… (More)
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2008
2008
PURPOSE GLI transcription factors mediate hedgehog signaling and have been implicated in several human malignancies, including… (More)
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Highly Cited
2004
Highly Cited
2004
Sonic hedgehog (Shh) binds to its receptor patched (PTCH), leading to the activation and repression of target genes via the GLI… (More)
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2004
2004
Sonic hedgehog (Hh) signaling plays a key role in epidermal development and skin cancer. Mutational inactivation of the tumor… (More)
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2004
2004
In stratified epidermis, activation of the Hh/Gli signal transduction pathway has been implicated in the control of cell… (More)
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Highly Cited
2002
Highly Cited
2002
Transgenic mouse models have provided evidence that activation of the zinc-finger transcription factor GLI1 by Hedgehog (Hh… (More)
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