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GLI2 protein, human

Known as: THP2 protein, human, Tax helper protein 2, human, TRE-binding protein 2, human 
Zinc finger protein GLI2 (1586 aa, ~168 kDa) is encoded by the human GLI2 gene. This protein plays a role in embryonic development and… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The transforming growth factor-beta (TGF-beta) pathway, which has both tumor suppressor and pro-oncogenic activities… 
Highly Cited
2007
Highly Cited
2007
Hedgehog (Hh) and transforming growth factor-beta (TGF-beta) family members are involved in numerous overlapping processes during… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Gli2 and Gli3 are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse. Gli3 mainly… 
Highly Cited
2006
Highly Cited
2006
Hedgehogs (Hhs) are key signaling regulators of stem cell maintenance and tissue patterning in embryos, and activating mutations… 
Review
2000
Review
2000
Approximately 1,000,000 epithelial skin cancers are diagnosed in the United States each year and most are basal cell carcinomas… 
Highly Cited
1999
Highly Cited
1999
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… 
Highly Cited
1998
Highly Cited
1998
The expression of genes involved in the Sonic Hedgehog signalling pathway, including Shh, Ptc, Smo, Gli1, Gli2 and Gli3, were… 
Highly Cited
1998
Highly Cited
1998
Foregut malformations (oesophageal atresia, tracheo-oesophageal fistula, lung anomalies and congenital stenosis of the oesophagus… 
Highly Cited
1997
Highly Cited
1997
The correct patterning of vertebrate skeletal elements is controlled by inductive interactions. Two vertebrate hedgehog proteins…