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DUSP1 protein, human

Known as: Mitogen-Activated Protein Kinase Phosphatase 1, MKP-1 protein, human, DUSP1 
Dual specificity protein phosphatase 1 (367 aa, ~39 kDa) is encoded by the human DUSP1 gene. This protein plays a role in the dephosphorylation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Exposure of macrophages to LPS elicits the production of proinflammatory cytokines, such as TNF-α, through complex signaling… Expand
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Highly Cited
2001
Highly Cited
2001
Glucocorticoids inhibit the proinflammatory activities of transcription factors such as AP‐1 and NF‐κB as well as that of diverse… Expand
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Highly Cited
2001
Highly Cited
2001
Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1/CL100) is an inducible nuclear dual specificity protein phosphatase… Expand
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Highly Cited
1999
Highly Cited
1999
Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the… Expand
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Highly Cited
1998
Highly Cited
1998
Activity-dependent changes in neuronal structure and synaptic remodeling depend critically on gene regulation. In an attempt to… Expand
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Highly Cited
1997
Highly Cited
1997
Angiotensin II type 2 (AT2) receptors are involved in the inhibition of cell proliferation as well as in apoptosis and neuronal… Expand
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Highly Cited
1996
Highly Cited
1996
The role of protein kinase C (PKC) in inflammation, mitogenesis, and differentiation has been deduced in part through the use of… Expand
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Highly Cited
1995
Highly Cited
1995
Irradiation of mammalian cells with short wavelength ultraviolet light (UVC) evokes a cascade of phosphorylation events leading… Expand
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Highly Cited
1995
Highly Cited
1995
Angiotensin II stimulates hypertrophic growth of vascular smooth muscle cells (VSMC) and activates many growth-promoting kinases… Expand
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Highly Cited
1995
Highly Cited
1995
MAP kinase (mitogen activated protein kinase) represents a ubiquitously expressed family of kinases whose long term activation… Expand
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