Skip to search formSkip to main contentSkip to account menu

DUSP1 protein, human

Known as: Mitogen-Activated Protein Kinase Phosphatase 1, MKP-1 protein, human, DUSP1 
Dual specificity protein phosphatase 1 (367 aa, ~39 kDa) is encoded by the human DUSP1 gene. This protein plays a role in the dephosphorylation of… 
National Institutes of Health

Related topics

Related topics

26 relations
CD40L Signaling PathwayCell ProliferationCellular Stress ResponseDUSP1 gene

Broader (1)

Dual Specificity Phosphatase 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo
Cigarette smoking promotes body weight reduction in humans while paradoxically also promoting insulin resistance (IR) and… 
Highly Cited
2012
Highly Cited
2012
Cluster Analysis of Obesity and Asthma Phenotypes
Background Asthma is a heterogeneous disease with variability among patients in characteristics such as lung function, symptoms… 
Highly Cited
2009
Highly Cited
2009
MAP KINASE PHOSPHATASE1 and PROTEIN TYROSINE PHOSPHATASE1 Are Repressors of Salicylic Acid Synthesis and SNC1-Mediated Responses in Arabidopsis[C][W]
Mitogen-activated protein (MAP) kinase phosphatases are important negative regulators of the levels and kinetics of MAP kinase… 
Highly Cited
2005
Highly Cited
2005
Essential Role for Mitogen-activated Protein (MAP) Kinase Phosphatase-1 in Stress-responsive MAP Kinase and Cell Survival Signaling*
Mitogen-activated protein kinase (MAPK) phosphatases (MKPs) constitute a family of 11 dual-specificity phosphatases that… 
Highly Cited
2001
Highly Cited
2001
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP‐1
Glucocorticoids inhibit the proinflammatory activities of transcription factors such as AP‐1 and NF‐κB as well as that of diverse… 
Highly Cited
2001
Highly Cited
2001
Distinct Binding Determinants for ERK2/p38α and JNK MAP Kinases Mediate Catalytic Activation and Substrate Selectivity of MAP Kinase Phosphatase-1* 210
Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1/CL100) is an inducible nuclear dual specificity protein phosphatase… 
Highly Cited
1996
Highly Cited
1996
The Selective Protein Kinase C Inhibitor, Ro-31-8220, Inhibits Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression, Induces c-Jun Expression, and Activates Jun N-terminal Kinase*
The role of protein kinase C (PKC) in inflammation, mitogenesis, and differentiation has been deduced in part through the use of… 
Highly Cited
1996
Highly Cited
1996
Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis.
Many mitogens and human oncogenes activate extracellular regulated kinases (ERKs), which in turn convey proliferation signals… 
Highly Cited
1995
Highly Cited
1995
Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts.
MAP kinase (mitogen activated protein kinase) represents a ubiquitously expressed family of kinases whose long term activation… 
Highly Cited
1995
Highly Cited
1995
Mitogen-activated Protein (MAP) Kinase Is Regulated by the MAP Kinase Phosphatase (MKP-1) in Vascular Smooth Muscle Cells
Angiotensin II stimulates hypertrophic growth of vascular smooth muscle cells (VSMC) and activates many growth-promoting kinases… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)