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DUSP1 gene

Known as: Dual Specificity Phosphatase 1 Gene, PTPN10, DUSP1 
This gene is a transcriptional target of TP53 protein and plays a role in cell cycle regulation.
National Institutes of Health

Related topics

Related topics

10 relations
DUSP1 protein, humanDUSP12 geneDephosphorylationDual Specificity Phosphatase 1

Narrower (1)

DUSP1 wt Allele

Broader (1)

Protein Serine/Threonine Phosphatase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Hyperglycaemia Stress-Induced Renal Injury is Caused by Extensive Mitochondrial Fragmentation, Attenuated MKP1 Signalling, and Activated JNK-CaMKII-Fis1 Biological Axis
Background/Aims: Hyperglycaemia stress-induced renal injury is closely associated with mitochondrial dysfunction through poorly… 
2015
2015
MAP kinase phosphatase 1 harbors a novel PTS1 and is targeted to peroxisomes following stress treatments.
2013
2013
ATR and MKP1 play distinct roles in response to UV-B stress in Arabidopsis.
Ultraviolet-B (UV-B) stress activates MAP kinases (MAPKs) MPK3 and MPK6 in Arabidopsis. MAPK activity must be tightly controlled… 
2010
2010
The extracellular signal-regulated kinase is involved in the effects of sildenafil on pulmonary vascular remodeling.
Pulmonary hypertension is a group of diseases comprising vascular constriction and obstructive changes of the pulmonary… 
Highly Cited
2008
Highly Cited
2008
Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP.
Glucocorticoids (GCs) are known to inhibit mitogen-activated protein kinase (MAPK) signaling. This has been suggested to involve… 
Highly Cited
2004
Highly Cited
2004
Cellular defense against H2O2-induced apoptosis via MAP kinase-MKP-1 pathway.
2004
2004
P53 transactivates the phosphatase MKP1 through both intronic and exonic p53 responsive elements
The tumor suppressor p53 protein can negatively regulate mitogen-activated protein kinase (MAPK) signaling via the induction of… 
Highly Cited
2000
Highly Cited
2000
CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin
Treatment of cells with cisplatin induces a sustained activation of the stress activated protein kinase SAPK/JNK and the mitogen… 
1995
1995
XCL100, an inducible nuclear MAP kinase phosphatase from Xenopus laevis: its role in MAP kinase inactivation in differentiated cells and its expression during early development.
We have cloned the Xenopus laevis homologue (XCL100) of the human CL100 (Thr/Tyr) MAP kinase phosphatase. Expression of the… 
1994
1994
Chromosomal localization of four human VH1-like protein-tyrosine phosphatases.
Four human protein-tyrosine phosphatase (PTPase) genes of the VH1-like subclass were cloned by low-stringency screening of a… 
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