Dual Specificity Phosphatase 1
Semantic Scholar uses AI to extract papers important to this topic.
Protein Ser/Thr phosphatase-1 (PP1) catalyzes the majority of eukaryotic protein dephosphorylation reactions in a highly… Expand Mitogen-activated protein kinase (MAPK) and PUF (for Pumilio and FBF [fem-3 binding factor]) RNA-binding proteins control many… Expand Activation of the mitogen-activated protein kinase (MAPK) cascade after Toll-like receptor stimulation enables innate immune… Expand TLR-induced innate immunity and inflammation are mediated by signaling cascades leading to activation of the MAPK family of Ser… Expand The p38 and JNK classes of mitogen-activated protein kinases (MAPKs) have evolutionarily conserved roles in the control of… Expand Mitogen‐activated protein kinases (MAPKs) are integral to the mechanisms by which cells respond to physiological stimuli and to a… Expand Our laboratory has recently demonstrated a role for the phosphatidylinositol 3-kinase-mediated inducible NO synthase (iNOS… Expand The crystal structure of the catalytic domain from the MAPK phosphatase Pyst1 (Pyst1–CD) has been determined at 2.35 Å. The… Expand Pathophysiological hypoxia is an important modulator of gene expression in solid tumors and other pathologic conditions. We… Expand Previously we showed that rat mesangial cells are normally resistant to tumor necrosis factor-α (TNF-α)-induced apoptosis. They… Expand