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Dual Specificity Phosphatase 1

Known as: MKP-1 Phosphatase, Map Kinase Phosphatase 1, 3CH134 Phosphatase 
A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It… 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Highly Cited
2007
Highly Cited
2007
Mitogen-activated protein kinase (MAPK) and PUF (for Pumilio and FBF [fem-3 binding factor]) RNA-binding proteins control many… 
Highly Cited
2006
Highly Cited
2006
Activation of the mitogen-activated protein kinase (MAPK) cascade after Toll-like receptor stimulation enables innate immune… 
Highly Cited
2006
Highly Cited
2006
TLR-induced innate immunity and inflammation are mediated by signaling cascades leading to activation of the MAPK family of Ser… 
Highly Cited
2006
Highly Cited
2006
Purpose: Excessive activity of the transcription factors known as signal transducers and activators of transcription (STAT… 
Highly Cited
2004
Highly Cited
2004
The p38 and JNK classes of mitogen-activated protein kinases (MAPKs) have evolutionarily conserved roles in the control of… 
Highly Cited
2004
Highly Cited
2004
Mitogen‐activated protein kinases (MAPKs) are integral to the mechanisms by which cells respond to physiological stimuli and to a… 
Highly Cited
2000
Highly Cited
2000
Our laboratory has recently demonstrated a role for the phosphatidylinositol 3-kinase-mediated inducible NO synthase (iNOS… 
Highly Cited
1999
Highly Cited
1999
The crystal structure of the catalytic domain from the MAPK phosphatase Pyst1 (Pyst1–CD) has been determined at 2.35 Å. The… 
Highly Cited
1999
Highly Cited
1999
Pathophysiological hypoxia is an important modulator of gene expression in solid tumors and other pathologic conditions. We…