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DS 4574

Known as: DS-4574 
National Institutes of Health

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2 relations

Broader (2)

PyrimidinesTriazoles

Papers overview

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1994
1994
Inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on compound 48/80-induced gastric mucosal lesions in rats
We evaluated the inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on rat gastric… 
1994
1994
Inhibitory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene receptor antagonism, on gastric acid secretion in rats.
1994
1994
Radioimmunoassay for DS-4574, an antiallergic agent: development, evaluation, and application to human plasma samples.
A sensitive radioimmunoassay (RIA) method for DS-4574, an antiallergic drug, in plasma has been developed. As the three major… 
1994
1994
Antisecretory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene antagonism, on gastric acid secretion in the pig
The antisecretory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene antagonism, on the hypersecretion of gastric… 
1993
1993
Effects of DS-4574, a new orally active antiallergic agent, in experimental allergic and inflammatory models.
The anti-allergic and anti-inflammatory activities of DS-4574, which possesses leukotriene antagonism and inhibits the release of… 
1993
1993
Inhibitory effect of DS-4574 on leukotriene- or antigen-induced bronchoconstriction in guinea pigs.
We studied the leukotriene (LT) antagonistic activity of DS-4574 in vivo and the inhibitory effect of this compound on antigen… 
1993
1993
Protective effect of DS-4574 on gastric mucosal injury induced by acidified ethanol in rats.
1992
1992
Antiallergic activity of 6-(2-cyclohexylethyl)-[1,3,4]thiadiazolo- [3,2-a]-1,2,3-triazolo-[4,5-d]pyrimidin-9(3H)-one (DS-4574) in rats.
The antiallergic activity of DS-4574 was evaluated in several commonly used rat models for allergic diseases. In passive… 
1992
1992
Effect of DS-4574, a novel peptidoleukotriene antagonist with mast cell stabilizing action, on acute gastric lesions and gastric secretion in rats.
DS-4574 is a peptidoleukotriene antagonist with mast cell stabilizing activity. In the present study, we studied the effects of… 
1991
1991
Antagonistic action of DS-4574 against leukotrienes in guinea-pig smooth muscle.
We investigated the effect of a new antiallergic agent, DS-4574, on the guinea-pig smooth muscle contractions induced by… 
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