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The measurement of gastric emptying in conscious rats by monitoring serial changes in serum acetaminophen level.
A method for evaluation of gastric emptying via monitoring serial serum levels of acetaminophen (APAP) as an indicator, without involving animal sacrifice, has been developed in conscious rats. WeExpand
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Inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on compound 48/80-induced gastric mucosal lesions in rats
We evaluated the inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on rat gastric mucosal lesions induced by compound 48/80 (C48/80: a mast cellExpand
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Enhancing effect of DQ-2511 on gastric emptying of spontaneously hypertensive rats.
The present study was designed to clarify the potential of DQ-2511 (3-[[[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl]carbamoyl]methyl] amino-N-methylbenzamide: ecabapide) as a gastroprokinetic agent inExpand
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Comparative evaluation of DQ‐2511, a novel gastroprokinetic agent, with cisapride in ameliorative action on experimentally induced delayed gastric emptying
We compared the main pharmacological effect of DQ‐2511 (3‐[[[2‐(3,4‐dimethoxyphenyl)‐ethyl]carbamoyl]methyl]amino ‐N‐ methylbenzamide), a novel gastroprokinetic agent, with that of cisapride. SingleExpand
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Pharmacological characteristics of DQ-2511 as a prokinetic agent.
The pharmacological characteristics of DQ-2511, a substituted benzamide (3-[[[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl]methyl] amino-N-methylbenzamide), as a prokinetic agent were studied.Expand
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Calculation of maximal removal rate of indocyanine green to measure hepatic functional mass in dogs by use of the nine-hour method.
OBJECTIVE To establish a versatile and reliable procedure for the determination of indocyanine green maximal removal rate (ICG Rmax) to measure hepatic functional mass in dogs within 9 hours (9-hourExpand
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Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors. III.
In order to improve the biological characteristics of DA-3934 (5), a novel gastrin/cholecystokinin (CCK)-B receptor antagonist, phenoxyacetic acid derivatives replacing theExpand
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Leukemic blasts detected by the Technicon H-1 blood cell counter.
The authors studied the usefulness of the flagging system of the Technicon H-1 Cell Counter using samples from 45 patients with acute leukemia, 24 with acute lymphoblastic leukemia (ALL), and 21 withExpand
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Protective effect of DS-4574 on gastric mucosal injury induced by acidified ethanol in rats.
We compared the protective effect of DS-4574, a peptidoleukotriene receptor antagonist with mast cell stabilizing action, on rat gastric mucosal injury induced by acidified ethanol to that ofExpand
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Effects of phalloidin on platelet release.
The effect on platelet of phalloidin, a reagent forming phalloidin-actin polymer, was studied. Phalloidin suppressed ATP release but did not affect aggregation after the stimulation with ADP orExpand
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