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DR1 gene

Known as: NC2-BETA, DR1, down-regulator of transcription 1 
This gene is involved in repression of transcription.
National Institutes of Health

Related topics

Related topics

6 relations
DR1 protein, humanHomo sapiensTranscriptional RegulationTranscriptional Repression

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DR1 wt Allele

Papers overview

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Highly Cited
2002
Highly Cited
2002
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells.
Exosomes are small vesicles (60-100 nm) secreted by various cell types upon the fusion of endosomal compartments with the plasma… 
Highly Cited
2001
Highly Cited
2001
Crystal Structure of Negative Cofactor 2 Recognizing the TBP-DNA Transcription Complex
Review
2000
Review
2000
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease.
Highly Cited
1997
Highly Cited
1997
An HLA-DR1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II Collagen
Rheumatoid arthritis (RA) is an autoimmune disease that is strongly associated with the expression of several HLA-DR haplotypes… 
Highly Cited
1995
Highly Cited
1995
Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II
The superantigen staphylococcal enterotoxin A (SEA) binds to major histocompatibility complex (MHC) class II molecules at two… 
Highly Cited
1994
Highly Cited
1994
Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer
Replication of the hepadnavirus genome occurs by reverse transcription of an RNA pregenome and is mediated by the viral… 
Highly Cited
1992
Highly Cited
1992
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor
Highly Cited
1991
Highly Cited
1991
On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.
We have investigated the interaction between DR1 molecules and the two antigenic peptides, tetanus toxoid 830-843 and… 
Highly Cited
1990
Highly Cited
1990
Peptide binding to HLA‐DR1: a peptide with most residues substituted to alanine retains MHC binding.
Major histocompatibility complex (MHC) glycoproteins play an important role in the development of an effective immune response… 
Highly Cited
1986
Highly Cited
1986
Biochemical and genetic evidence for the hepatitis B virus replication strategy.
Hepatitis B viruses synthesize their open circular DNA genomes by reverse transcription of an RNA intermediate. The details of… 
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