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DR1 gene

Known as: NC2-BETA, DR1, down-regulator of transcription 1 
This gene is involved in repression of transcription.
National Institutes of Health

Related topics

Related topics

6 relations
DR1 protein, humanHomo sapiensTranscriptional RegulationTranscriptional Repression

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DR1 wt Allele

Papers overview

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Highly Cited
1997
Highly Cited
1997
Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81–90) region
Association of the invariant chain (Ii) with MHC class II α and β chains is central for their functionality and involves the Ii… 
Highly Cited
1994
Highly Cited
1994
Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding.
Superantigens bind to major histocompatibility complex class II molecules on antigen-presenting cells and stimulate T cells… 
Highly Cited
1992
Highly Cited
1992
Identification of HLA-DR1 beta chain residues critical for binding staphylococcal enterotoxins A and E
Superantigens are thought to make external contacts with major histocompatibility complex (MHC) class II molecules and with the V… 
Highly Cited
1992
Highly Cited
1992
Human T cells cannot act as autonomous antigen-presenting cells, but induce tolerance in antigen-specific and alloreactive responder cells
The ability of two HLA-DR-expressing human T cell clones to function as antigen-presenting cells (APC) was investigated using… 
Highly Cited
1992
Highly Cited
1992
Oligonucleotide geriotyping of HLA polymorphism on microtitre plates
Highly Cited
1991
Highly Cited
1991
Truncation analysis of several DR binding epitopes.
Peptide regions crucial for binding to four different DR alleles (DR1, DR2, DR5, and DR52a) have been localized in five unrelated… 
Highly Cited
1989
Highly Cited
1989
Co-recognition of endogenous antigens with HLA-DR1 by alloreactive human T cell clones.
The fine specificity of anti-HLA-DR1 alloreactive, human T cells was investigated by using DR1-expressing human and murine… 
Highly Cited
1985
Highly Cited
1985
DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype.
Two HLA class II beta-chain clones from a cell line homozygous for the DR1 haplotype have been characterized and sequenced. They… 
Highly Cited
1985
Highly Cited
1985
HLA class II restriction repertoire of antigen-specific T cells. I. The main restriction determinants for antigen presentation are associated with HLA-D/DR and not with DP and DQ.
Highly Cited
1984
Highly Cited
1984
Serological and cellular definition of a new HLA-DR associated determinant, MC1, and its association with rheumatoid arthritis.
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