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DR1 wt Allele

Known as: Down-Regulator of Transcription 1, TBP-Binding (Negative Cofactor 2) wt Allele, NC2, NC2-Beta 
Human DR1 wild-type allele is located in the vicinity of 1p22.1 and is approximately 17 kb in length. This allele, which encodes TATA-binding protein… 
National Institutes of Health

Related topics

Related topics

7 relations
1p22.1DR1 protein, humanHomo sapiensTranscriptional Regulation

Broader (1)

DR1 gene

Papers overview

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Highly Cited
2002
Highly Cited
2002
Proteasome, Transporter Associated with Antigen Processing, and Class I Genes in the Nurse Shark Ginglymostoma cirratum: Evidence for a Stable Class I Region and MHC Haplotype Lineages1
Cartilaginous fish (e.g., sharks) are derived from the oldest vertebrate ancestor having an adaptive immune system, and thus are… 
2002
2002
The NC2 alpha and beta subunits play different roles in vivo.
NC2 is a heterodimeric regulator of transcription that plays both positive and negative roles in vivo. Here we show that the… 
2000
2000
The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear…
Activation of class II gene transcription may involve alleviation of transcription repression as well as stimulation of the… 
Highly Cited
1998
Highly Cited
1998
Interplay of Positive and Negative Regulators in Transcription Initiation by RNA Polymerase II Holoenzyme
ABSTRACT Activation of protein-encoding genes involves recruitment of an RNA polymerase II holoenzyme to promoters. Since the… 
Highly Cited
1998
Highly Cited
1998
Differential expression of TrkC catalytic and noncatalytic isoforms suggests that they act independently or in association
Members of the trk gene family encode neurotrophin receptors. The trkC locus encodes multiple neurotrophin‐3 catalytic and… 
Highly Cited
1993
Highly Cited
1993
Complete primary structure of chicken collagen XIV.
We have isolated and characterized several overlapping cDNA clones for chicken collagen XIV which span a total of 6.5 kpb. These… 
1993
1993
Location and alternative splicing of type XIII collagen RNA in the early human placenta.
BACKGROUND Type XIII collagen is widely distributed in the fetus. It is characterized by complex alternative splicing of its… 
Highly Cited
1991
Highly Cited
1991
Type XIV collagen, a new homotrimeric molecule extracted from fetal bovine skin and tendon, with a triple helical disulfide-bonded domain homologous to type IX and type XII collagens.
Previously undescribed disulfide-bonded collagenous pepsin-derived fragments have been isolated from fetal calf tendon and skin… 
1991
1991
The alpha 1 (VIII) collagen gene is homologous to the alpha 1 (X) collagen gene and contains a large exon encoding the entire triple helical and carboxyl-terminal non-triple helical domains of the…
We recently cloned and sequenced alpha 1 (VIII) collagen cDNAs and demonstrated that type VIII collagen is a short-chain collagen… 
1990
1990
Identification of the cleavage sites by a hemorrhagic metalloproteinase in type IV collagen.
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