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DNA ligase

Known as: ATP, Polydeoxyribonucleotide Synthase, DNA joinase, Synthase ATP, Polydeoxyribonucleotide 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Abstract DNA library preparation for high-throughput sequencing of genomic DNA usually involves ligation of adapters to double… 
Highly Cited
2011
Highly Cited
2011
Recent studies have implicated a poorly defined alternative pathway of nonhomologous end joining (alt-NHEJ) in the generation of… 
Highly Cited
2009
Highly Cited
2009
ABSTRACT Nonhomologous end-joining represents the major pathway used by human cells to repair DNA double-strand breaks. It relies… 
Highly Cited
2003
Highly Cited
2003
Pyridochromanones were identified by high throughput screening as potent inhibitors of NAD+-dependent DNA ligase from Escherichia… 
Review
2002
Review
2002
SummaryBy catalyzing the joining of breaks in the phosphodiester backbone of duplex DNA, DNA ligases play a vital role in the… 
Highly Cited
2000
Highly Cited
2000
The DNA-dependent protein kinase (DNA-PK), consisting of Ku and the DNA-PK catalytic subunit (DNA-PKcs), and the DNA ligase IV… 
Highly Cited
2000
Highly Cited
2000
Rejoining of single- and double-strand breaks (DSBs) introduced in DNA during replication, recombination, and DNA damage is… 
Highly Cited
1998
Highly Cited
1998
The XRCC4 gene is required for the repair of DNA double-strand breaks in mammalian cells. Without XRCC4, cells are hypersensitive… 
Highly Cited
1997
Highly Cited
1997
Eukaryotic DNA ligases are ATP-dependent DNA strand-joining enzymes that participate in DNA replication, repair, and… 
Highly Cited
1996
Highly Cited
1996
The DNA ligase from Thermus thermophilus (Tth DNA ligase) seals single-strand breaks (nicks) in DNA duplex substrates. The…