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DNA ligase

Known as: ATP, Polydeoxyribonucleotide Synthase, DNA joinase, Synthase ATP, Polydeoxyribonucleotide 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

DNA LigasesDNA Repair EnzymesPolynucleotide Ligases
LIG4 geneLIG4 protein, humandamaged DNA binding

Papers overview

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Highly Cited
2010
Highly Cited
2010
Combination of DNA ligase reaction and gold nanoparticle-quenched fluorescent oligonucleotides: a simple and efficient approach for fluorescent assaying of single-nucleotide polymorphisms.
A new fluorescent sensing approach for detection of single-nucleotide polymorphisms (SNPs) is proposed based on the ligase… 
2005
2005
Using molecular beacon to monitor activity of E. coli DNA ligase.
NAD(+)-dependent DNA ligase has been widely used in gene diagnostics for disease-associated mutation detection and has proved to… 
2002
2002
Substrate recognition and fidelity of strand joining by an archaeal DNA ligase.
We have previously identified a DNA ligase (LigTk) from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1. The enzyme… 
Highly Cited
2001
Highly Cited
2001
Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus
ABSTRACT A Staphylococcus aureus mutant conditionally defective in DNA ligase was identified by isolation of complementing… 
2001
2001
Identification of a Mutated DNA Ligase IV Gene in the X-ray-hypersensitive Mutant SX10 of Mouse FM3A Cells*
The mouse carcinoma cell line SX10 is a hypersensitive mutant to x-rays and bleomycin. An earlier complementation test suggests… 
Highly Cited
2000
Highly Cited
2000
A DNA Ligase from a Hyperthermophilic Archaeon with Unique Cofactor Specificity
ABSTRACT A gene encoding DNA ligase (ligTk) from a hyperthermophilic archaeon, Thermococcus kodakaraensisKOD1, has been cloned… 
Highly Cited
1998
Highly Cited
1998
DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains
1997
1997
Ligation of RNA-containing duplexes by vaccinia DNA ligase.
Vaccinia virus DNA ligase repairs nicked duplex DNA substrates consisting of a 5'-phosphate-terminated strand and a 3'-hydroxyl… 
Highly Cited
1991
Highly Cited
1991
In vitro mutagenesis and functional expression in Escherichia coli of a cDNA encoding the catalytic domain of human DNA ligase I.
Human cDNAs encoding fragments of DNA ligase I, the major replicative DNA ligase in mammalian cells, have been expressed as lacZ… 
1988
1988
DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.
The ability to alter DNA tertiary structure of ten anthracycline derivatives whose antitumor potency is known was studied by an… 
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