DNA ligase

Known as: ATP, Polydeoxyribonucleotide Synthase, DNA joinase, Synthase ATP, Polydeoxyribonucleotide 
 
National Institutes of Health

Papers overview

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2009
2009
Nonhomologous end-joining represents the major pathway used by human cells to repair DNA double-strand breaks. It relies on the… (More)
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Highly Cited
2006
Highly Cited
2006
DNA sliding clamps encircle DNA and provide binding sites for many DNA-processing enzymes. However, it is largely unknown how… (More)
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2005
2005
Our recent demonstration that DNA polymerase X (Pol X), the DNA repair polymerase encoded by the African swine fever virus (ASFV… (More)
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Review
2002
Review
2002
By catalyzing the joining of breaks in the phosphodiester backbone of duplex DNA, DNA ligases play a vital role in the diverse… (More)
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Highly Cited
2000
Highly Cited
2000
The DNA-dependent protein kinase (DNA-PK), consisting of Ku and the DNA-PK catalytic subunit (DNA-PKcs), and the DNA ligase IV… (More)
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Highly Cited
1999
Highly Cited
1999
XR-1 is a CHO mutant cell line defective in double strand break repair and V(D)J recombination. These defects are due to a… (More)
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Highly Cited
1998
Highly Cited
1998
The covalent rejoining of DNA ends at single-stranded or double-stranded DNA breaks is catalyzed by DNA ligases. Four DNA ligase… (More)
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Highly Cited
1998
Highly Cited
1998
The XRCC4 gene is required for the repair of DNA double-strand breaks in mammalian cells. Without XRCC4, cells are hypersensitive… (More)
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Highly Cited
1997
Highly Cited
1997
Eukaryotic DNA ligases are ATP-dependent DNA strand-joining enzymes that participate in DNA replication, repair, and… (More)
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Highly Cited
1996
Highly Cited
1996
The DNA ligase from Thermus thermophilus (Tth DNA ligase) seals single-strand breaks (nicks) in DNA duplex substrates. The… (More)
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