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DNA ligase

Known as: ATP, Polydeoxyribonucleotide Synthase, DNA joinase, Synthase ATP, Polydeoxyribonucleotide 
 
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Abstract DNA library preparation for high-throughput sequencing of genomic DNA usually involves ligation of adapters to double… Expand
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Highly Cited
2011
Highly Cited
2011
Recent studies have implicated a poorly defined alternative pathway of nonhomologous end joining (alt-NHEJ) in the generation of… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT Nonhomologous end-joining represents the major pathway used by human cells to repair DNA double-strand breaks. It relies… Expand
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Highly Cited
2007
Highly Cited
2007
DNA non-homologous end-joining (NHEJ) is a major mechanism for repairing DNA double-stranded (ds) breaks in mammalian cells. Here… Expand
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Highly Cited
2006
Highly Cited
2006
DNA sliding clamps encircle DNA and provide binding sites for many DNA-processing enzymes. However, it is largely unknown how… Expand
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Highly Cited
2000
Highly Cited
2000
The DNA-dependent protein kinase (DNA-PK), consisting of Ku and the DNA-PK catalytic subunit (DNA-PKcs), and the DNA ligase IV… Expand
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Highly Cited
1999
Highly Cited
1999
XR-1 is a CHO mutant cell line defective in double strand break repair and V(D)J recombination. These defects are due to a… Expand
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Highly Cited
1998
Highly Cited
1998
The XRCC4 gene is required for the repair of DNA double-strand breaks in mammalian cells. Without XRCC4, cells are hypersensitive… Expand
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Highly Cited
1997
Highly Cited
1997
Eukaryotic DNA ligases are ATP-dependent DNA strand-joining enzymes that participate in DNA replication, repair, and… Expand
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Highly Cited
1996
Highly Cited
1996
The DNA ligase from Thermus thermophilus (Tth DNA ligase) seals single-strand breaks (nicks) in DNA duplex substrates. The… Expand
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