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DNA Polymerase Inhibitors

Known as: DNA Polymerase Inhibitor, Inhibitors, DNA Polymerase, Polymerase Inhibitors, DNA 
Any substance that inhibits DNA polymerase, an enzyme that catalyzes the addition of deoxyribonucleotide residues to the end of a DNA molecule… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

Nucleic Acid Synthesis Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Subcellular Localization and Ser-137 Phosphorylation Regulate Tumor-suppressive Activity of Profilin-1*
Background: The actin-binding protein profilin-1 is a eukaryotic protein essential for growth, with poorly understood antitumor… 
2007
2007
Irofulven induces replication-dependent CHK2 activation related to p53 status.
2005
2005
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
Epolactaene (compound 1), a neuritogenic compound found in human neuroblastoma cells, was found to show anti-inflammatory… 
1996
1996
Potentiation of cisplatin cytotoxicity by 9-aminocamptothecin.
Camptothecin (CPT) derivatives are presently in ongoing Phase I/II clinical trials. The interactions between 9-aminocamptothecin… 
1994
1994
Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors.
The effect of the DNA polymerase inhibitors adenine 9-beta-arabinofuranoside (ara-A), cytosine 1-beta-arabinofuranoside (ara-C… 
1991
1991
Inhibition of DNA repair and the enhancement of cytotoxicity of alkylating agents
DNA damage was evaluated by flow cytometric (FCM) analysis of cells treated with L‐phenylalanine mustard (L‐PAM) and stained with… 
1990
1990
The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis.
1987
1987
Cell cycle dependent activities of DNA polymerases alpha and delta in Chinese hamster ovary cells.
The activities of DNA polymerases alpha and delta, in extracts from Chinese hamster ovary (CHO) cells, were assayed in order to… 
Highly Cited
1981
Highly Cited
1981
Physical mapping of drug resistance mutations defines an active center of the herpes simplex virus DNA polymerase enzyme
The genome structures of herpes simplex virus type 1 (HSV-1)/HSV-2 intertypic recombinants have been previously determined by… 
1974
1974
Identification of a polypeptide DNA polymerase inhibitor responsible for ribonuclease inhibition of an endogenous DNA polymerase reaction.
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