DNA Breaks, Single-Stranded

Known as: Single Stranded DNA Breaks, Single-Stranded DNA Break, Nick, DNA 
A DNA Single Strand Break involves one or more disruptions of the covalent linkages among phosphodeoxyribose moieties within the sugar-phosphate… (More)
National Institutes of Health

Related topics

Related topics

4 relations
Chromosome StructuresDNA RepairSingle Strand Break Repairaspects of radiation effects

Papers overview

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Review
2017
Review
2017
DNA Origami: Scaffolds for Creating Higher Order Structures.
DNA has become one of the most extensively used molecular building blocks for engineering self-assembling materials. DNA origami… (More)
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Highly Cited
2008
Highly Cited
2008
Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends
Formation of single-strand DNA (ssDNA) tails at a double-strand break (DSB) is a key step in homologous recombination and DNA… (More)
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Highly Cited
2008
Highly Cited
2008
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
DNA ends exposed after introduction of double-strand breaks (DSBs) undergo 5′–3′ nucleolytic degradation to generate single… (More)
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Highly Cited
2006
Highly Cited
2006
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
We show that DNA double-strand breaks (DSBs) induce complex subcompartmentalization of genome surveillance regulators. Chromatin… (More)
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Highly Cited
2003
Highly Cited
2003
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
Activation-induced cytidine deaminase (AID) is a protein required for B cells to undergo class switch recombination and somatic… (More)
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Highly Cited
2000
Highly Cited
2000
Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.
Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel… (More)
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Review
1997
Review
1997
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism.
Replication protein A [RPA; also known as replication factor A (RFA) and human single-stranded DNA-binding protein] is a single… (More)
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Highly Cited
1995
Highly Cited
1995
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint.
A cdc13 temperature-sensitive mutant of Saccharomyces cerevisiae arrests in the G2 phase of the cell cycle at the restrictive… (More)
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Highly Cited
1989
Highly Cited
1989
High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier
A method, using LiAc to yield competent cells, is described that increased the efficiency of genetic transformation of intact… (More)
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Highly Cited
1989
Highly Cited
1989
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.
A series of yeast shuttle vectors and host strains has been created to allow more efficient manipulation of DNA in Saccharomyces… (More)
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