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Single Strand Break Repair

Known as: Single-Strand Break Repair 
The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair. [http… 
National Institutes of Health

Related topics

Related topics

12 relations
Cell SurvivalDNA Breaks, Single-StrandedFTO geneFTO wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility
The consequences of PARP-1 disruption or inhibition on DNA single-strand break repair (SSBR) and radio-induced lethality were… 
Highly Cited
2005
Highly Cited
2005
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
Spinocerebellar ataxia with axonal neuropathy-1 (SCAN1) is a neurodegenerative disease that results from mutation of tyrosyl… 
Highly Cited
2005
Highly Cited
2005
XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair.
Highly Cited
2004
Highly Cited
2004
The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks
Highly Cited
2003
Highly Cited
2003
Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
Highly Cited
2002
Highly Cited
2002
Central Role for the XRCC1 BRCT I Domain in Mammalian DNA Single-Strand Break Repair
ABSTRACT The DNA single-strand break repair (SSBR) protein XRCC1 is required for genetic stability and for embryonic viability… 
Review
2001
Review
2001
Mammalian DNA single‐strand break repair: an X‐ra(y)ted affair
The genetic stability of living cells is continuously threatened by the presence of endogenous reactive oxygen species and other… 
Review
2001
Review
2001
Protein-protein interactions during mammalian DNA single-strand break repair.
The genetic stability of living cells is continually threatened by endogenous reactive oxygen species and other genotoxic… 
Highly Cited
1999
Highly Cited
1999
Solution structure of the single-strand break repair protein XRCC1 N-terminal domain
XRCC1 functions in the repair of single-strand DNA breaks in mammalian cells and forms a repair complex with β-Pol, ligase III… 
Highly Cited
1996
Highly Cited
1996
Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells.
Wortmannin, an inhibitor of p110 PI 3-kinase, also inhibits DNA-dependent protein kinase, which is known to mediate DNA double… 
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